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High-pressure preparative LC system with UV-Vis detection (200–800 nm), integrated autosampler, and multi-column switching.
The Teledyne ISCO ACCQPrep HP150 is a high-performance preparative liquid chromatography system designed for automated compound purification, peptide isolation, and reaction cleanup, widely used in biotechnology and molecular diagnostics workflows. Its fully integrated platform features a 150 mL/min maximum flow rate with ±2% accuracy and supports pressures up to 6000 psi (414 bar), enabling robust bioprocessing and biopharmaceutical purification applications.
Key components include the ACCQPrep AI 5 AutoInjector for precise, programmable sample introduction, the AS 2x2 autosampler module for unattended queued injections, and the ACCQPrep CSV 4 column selector valve alongside the SSV 2x3 solvent selector valve module for flexible solvent and column switching. UV-Vis detection covers 200 to 800 nm wavelengths with ±5 nm increments, facilitating absorbance tracking critical in synthetic biology and molecular cloning purification steps.
The system’s high-pressure, dual-piston reciprocating pumps provide accurate gradient formation (linear, step, isocratic) with ±1% gradient linearity, ensuring stable mixing and consistent solvent delivery optimized for fraction collection workflows. Designed for ambient operation at 20–40°C, the platform allows internal and external fraction collection and supports multiple solvents in up to 2 x 3 configurations.
Technically validated for flow accuracy, sample handling reproducibility, solvent routing, UV lamp performance, and gradient stability, this system ensures reliable preparative chromatography with minimal carryover or cross-fraction contamination—essential for demanding biotechnology, peptide purification, and natural product isolation applications.
Dimensions are 27.5" x 14" x 20", weighing 93.2 lbs, with the autosampler module measuring 18.9" x 14" x 19.3" and 27.3 lbs. Power requirements are 100–240 VAC, 50/60 Hz.
This setup is popular among researchers in biomedical engineering, cell imaging, and clinical diagnostics requiring accurate, unattended prep-scale purification with integrated UV-Vis absorbance tracking and multi-column solvents management. It is critical in biopharmaceutical production pipelines and molecular biology workflows for automated and reproducible purification of complex samples.
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We're an independent team based in The Netherlands, working with research labs and procurement teams across Europe and worldwide.
With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.
Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.
Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.
Two to six weeks, depending on refurbishment scope and whether calibration is included.
We ship to 38 countries. Crating and customs handling are quoted with the instrument.
Tell us what you need and a scientist finds it for you, usually within the hour.
Last updated 1 November 2026
The middle half of the 226 with a price runs from €52 to €1,497.
