Shimadzu Prominence HPLC System with Degasser, Binary Pump, Column Oven, and Autosampler

The Shimadzu Prominence HPLC System is an integrated analytical solution widely used in biotechnology, molecular diagnostics, and bioprocessing for precise separation and quantification of chemical compounds. This system comprises:

• DGU-20A5 Degasser: Equipped with 5 channels, providing effective solvent degassing with an internal volume of 380 µL, operational within 4°C to 35°C to maintain solvent integrity during liquid chromatography workflows.
• LC-20AT Pump: Features a serial double-plunger design ensuring continuous, pulse-free flow with a flow rate range of 0.001 to 10.000 mL/min, optimized for high-precision gradient elution critical in molecular biology and synthetic biology applications. The pump also includes improved bubble removal technology enhancing system reliability.
• CTO-20A Column Oven: Offers precise temperature control from 10°C above ambient up to 85°C with ±0.1°C accuracy, accommodating up to 10 columns with maximum length of 25 cm. The temperature range supports biomolecule stability during chromatography separation processes essential in biopharmaceutical production pipelines.
• SIL-20AC ht Autosampler: Enables injections from 0.1 to 100 µL volumes with a sample capacity of 70 vials (1.5 mL) plus 10 control vials (1.5 mL), facilitating high-throughput sample processing required in clinical diagnostics and live-cell imaging studies.

This system’s modular configuration and reliable performance make it critical for advanced analytical tasks in biotechnology research, including gene editing product analysis, bioprocessing quality control, and synthetic biology research. Its precision and versatility support highly reproducible chromatography data in biomanufacturing and molecular cloning workflows.