Thermo Scientific CellInsight CX7 HCS Automated High Content Screening Microscope System

The Thermo Scientific CellInsight CX7 HCS High Content Screening Platform is an automated microscopy system designed for high-throughput biological imaging and quantitative cellular analysis. Optimized for biomedical research and biotechnological applications, it supports widefield fluorescence, brightfield, and confocal imaging modalities enabling versatile assay workflows such as molecular diagnostics, phenotypic profiling, and high-content RNAi/CRISPR screening.

Key technical specifications include:

• Optical configuration: Infinity corrected with a 3-position automated objective changer.
• Objectives supplied: Olympus 10x (NA 0.40), 20x (NA 0.45), and 40x (NA 0.60) for multi-scale resolution and detail.
• Imaging modes: Widefield fluorescence using a 7-color high-output LED light source (405, 450, 488, 561, 594, 647, 785 nm wavelengths), brightfield with RGB and amber LED illumination plus white light, and confocal imaging powered by Crest Optics spinning pinhole disks (10,000 RPM; 40 µm / 70 µm pinhole sizes).
• Sample compatibility: Supports standard multi-well plates (96-, 384-, 1536-well formats) and microscope slides (up to 4 on 4-position slide adapter).
• Autofocus and exposure: Integrated laser autofocus and manual exposure controls for precise imaging conditions with sub-micron focus step resolution.
• Software: Includes HCS Studio 5 software installed on the accompanying desktop PC for data acquisition, image visualization, and quantitative analysis essential for biotechnology workflows such as bioprocessing and synthetic biology research.
• Barcode reader: Supports multiple symbologies (UPC-A, EAN, Code 39, ISBT 128) facilitating sample tracking in molecular diagnostics pipelines.
• Automation optionality: Compatible with Orbitor RS2 microplate mover for enhanced throughput automation.

This HCS platform is critical in biopharmaceutical production pipelines and widely adopted in molecular biology laboratories for phenotypic screening, live-cell imaging, and high-content RNAi/CRISPR screens. Its comprehensive optics and multi-wavelength LED illumination system make it suitable for fluorescence analysis and quantitative cell-based assays in neuroscience, oncology, and cell imaging research domains.

The instrument undergoes stringent testing including power, communication, autofocus, objective selection, image acquisition quality (brightfield, widefield, confocal), and plate movement verification by certified service engineers. It is available with a continental US warranty and international support including remote setup and training.

Ideal for research institutions and biotech companies requiring robust, high-throughput imaging integrated with versatile assay capabilities. The CellInsight CX7 HCS platform combines automated high content screening, multi-mode fluorescence imaging, and quantitative analysis facilitating essential workflows in molecular cloning, gene editing, and synthetic biology studies.