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Procurable · sourced on request

Leica TCS SP2

UsedLeicaConfocal microscopesNetherlands
Procurable

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Laser Lines
405, 430, 458, 476, 488, 496, 514, 561, 633 nm
Number of Photomultiplier Tubes (PMTs)
3
Acquisition Modes
xyz, xzy, xt, xyt, xzt, xyzt, xyλ, xzλ, xyλt, xyλz
Scan Speeds
Variable and Resonant; 1 to 16,000 Hz
Objectives
1.6x Dry N.A. 0.05; 10x Dry N.A. 0.30; 20x Dry N.A. 0.40; 40x Dry N.A. 0.60; 40x Oil N.A. 1.25; 63x Oil N.A. 1.40
Availability
Procurable
Lead time
Confirmed with your quote
All 20 specifications
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Specifications 20

Brands
Leica
New/Used
Used
Laser Lines
405, 430, 458, 476, 488, 496, 514, 561, 633 nm
Number of Photomultiplier Tubes (PMTs)
3
Acquisition Modes
xyz, xzy, xt, xyt, xzt, xyzt, xyλ, xzλ, xyλt, xyλz
Scan Speeds
Variable and Resonant; 1 to 16,000 Hz
Objectives
1.6x Dry N.A. 0.05; 10x Dry N.A. 0.30; 20x Dry N.A. 0.40; 40x Dry N.A. 0.60; 40x Oil N.A. 1.25; 63x Oil N.A. 1.40
Temperature Control
Home-built microscope incubator; PeCon heated stage
Humidity Range
10% to 80% (non-condensing)
Operating Temperature Range
18°C to 30°C
Weight of Confocal Unit
75 kg
Weight of Microscope
45 kg
System Weight
120 kg
Static Floor Load
150 kg/m²
Power Supply
100 - 240 V, 50/60 Hz
Power Consumption
800 VA
Detection Range
400 to 800 nm
Data Output
Digital; via computer interface
Availability
Procurable
Lead time
Confirmed with your quote

Product description

Confocal microscope with multiple laser lines and AOBS spectral detection for high-res fluorescent imaging.

The Leica TCS SP2 is a confocal laser scanning microscope designed for high-resolution imaging of fluorescently labelled specimens. Introduced in 1999, this instrument has been instrumental in advancing research across various scientific disciplines.

Key features include:

  • Multiple laser lines: Equipped with lasers at 405, 458, 476, 488, 514, 543, and 633 nm, facilitating excitation of a broad range of fluorophores.
  • Spectral detection: Features acousto-optical beam splitter (AOBS) technology, allowing flexible and efficient separation of emission spectra without traditional filters.
  • Versatile objectives: Offers a range of objectives, including water immersion lenses, suitable for live-cell imaging applications.
  • Advanced imaging modes: Supports techniques such as fluorescence recovery after photobleaching (FRAP), fluorescence resonance energy transfer (FRET), and time-lapse imaging, enhancing dynamic studies of cellular processes.

The Leica TCS SP2 has been widely utilised in fields such as cell biology, neuroscience, biochemistry, and biomedical research. Its applications range from studying protein localisation and interactions to analysing cellular dynamics and morphology.

Commonly found in university laboratories, biomedical research centres, and clinical research facilities, this microscope has been a cornerstone in imaging core facilities worldwide. Although Leica ceased manufacturing the SP2 in 2006, many units remained operational in research institutions for several years thereafter.

The Leica TCS SP2's robust design and versatile capabilities have made it a valuable tool for researchers seeking high-quality confocal imaging solutions.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 30 October 2026