Thermo Fisher Scientific CTS Xenon Electroporation Instrument for Scalable Cell Processing

The Thermo Fisher Scientific CTS Xenon Electroporation Instrument is a high-efficiency benchtop electroporation device designed to support scalable and reproducible cell processing workflows, particularly suited for advanced biotechnology and molecular diagnostics applications. Its key features and technical specifications include:

• Electroporation Parameters:
• Pulse voltage range: 500–2,500 V
• Pulse width: 1–30 ms
• Pulse interval: 500–1,000 ms
• Number of pulses: 1–10
• Sample Processing Capacity:
• Recommended cell concentration: 20 x 10⁶ to 100 x 10⁶ cells/mL
• Electroporation volumes: 1 mL and scalable 5–25 mL range
• Electroporation chamber volume: 1 mL
• Run time for larger volumes (5–25 mL): 7–22 minutes
• Integrated Fluidics System:
• Peristaltic pump for precise sample handling and transfer
• Cell mixer rotation speed at 60 rpm to maintain homogeneity during electroporation
• Temperature Control:
• Peltier-based precooling technology with adjustable temperature settings from 10°C to 30°C to protect cell viability and optimize transfection efficiency
• Safety and Maintenance:
• Built-in safety interlocks and diagnostics for operational reliability
• Easy access design for cleaning and preventive maintenance
• Physical Configuration:
• Compact benchtop design for controlled laboratory environments
• Dimensions (door open): 43.1 x 26.5 x 21.2 inches (109.5 x 67.4 x 53.9 cm)
• Weight: 154.3 lb (70 kg)

Applications of this instrument are fundamental within biotechnology, immunotherapy development, and clinical translational research, including:

• Ex vivo cell transfection workflows for cell and gene therapy manufacturing
• Electroporation of sensitive primary cell types such as T cells and stem cells
• Non-viral nucleic acid delivery (DNA, RNA, mRNA, CRISPR components) critical for gene editing and synthetic biology
• High-efficiency functional cell modification for CAR-T cell therapy and molecular cloning workflows

The system supports precise control of electrical pulses with consistent reproducibility, making it essential equipment for bioprocessing, molecular diagnostics, and biopharmaceutical production pipelines. The CTS Xenon Electroporation Instrument integrates advanced technology and reliable operation to meet the stringent demands of modern biomedical engineering and live-cell imaging research environments.

Included with the instrument are the standard power cord and full service verification by technical specialists, ensuring the device arrives fully functional with warranty and technical support options. Its compact size and robust build make it popular among research laboratories and biomanufacturing facilities focused on scalable gene editing and cell therapy development.

This electroporation system is widely adopted for applications requiring precise electrical parameter control, sample handling, and temperature regulation, contributing significantly to the efficiency and success of clinical and translational biotechnology projects.