Covaris R230 Focused Ultrasonicator for Automated DNA/RNA Shearing and Sample Preparation

The Covaris R230 Focused Ultrasonicator is an advanced acoustic shearing system engineered for high-throughput, precise fragmentation of DNA, RNA, and chromatin in molecular biology and biotechnological research. It enables efficient and reproducible sample preparation essential for next-generation sequencing (NGS) library construction, transcriptomics, ChIP-seq, and FFPE tissue processing workflows.

Key specifications and features include:

• Treatment Power: 0.5 to 110 W average incident power, peak incident power (PIP) up to 450 W
• Operating Temperature Range: 5°C to 40°C, maintained by integrated Covaris Water Conditioning System 3.0 (WCS 3.0)
• Sample Capacity: Simultaneous processing of up to 16 samples; compatible with batch sizes of 96 or 384 samples using appropriate consumable plates
• Supported Sample Volumes: 5 to 200 µL, tailored for NGS sample volume requirements
• Integration Capability: Designed for on-deck placement to integrate seamlessly with robotic liquid handling platforms for walk-away, automated workflows
• Control Interface: Includes eBox control unit with SonoLab software providing centralized, remote instrument operation and real-time monitoring
• Consumables Compatibility: Supports a wide range of Covaris consumables such as AFA-TUBE TPX strips and plates, microTUBE strips, and multiwell consumable formats, essential for accommodating diverse sample types and assay protocols
• Power Requirements: 100-240 VAC, 500 VA, 50-60 Hz, suitable for global laboratory environments

The R230 system employs Adaptive Focused Acoustics (AFA) technology, which delivers uniform cavitation energy ensuring precise and reproducible DNA shearing and RNA fragmentation critical in molecular diagnostics, gene editing preparation, bioprocessing sample prep, and synthetic biology research applications. The robust design supports continuous operation in demanding laboratory settings, minimizing user intervention while maximizing throughput and consistency.

This instrument is widely adopted in research fields including biotechnology, clinical diagnostics, and biopharmaceutical production pipelines where reliable and scalable sample processing is paramount. It is critical for applications such as molecular cloning workflows, transcriptome analysis, epigenomics, and chromatin immunoprecipitation sequencing.

Included with purchase:

• Covaris R230 Focused Ultrasonicator system
• Covaris Water Conditioning System 3.0 for temperature stabilization and water degassing
• Computer equipped with current SonoLab software for instrument control and protocol customization
• Communication and power cables

Note: Consumable tube racks, waveguides, and specific consumables are application-dependent and sold separately.

The instrument is fully tested and serviced, ensuring operational integrity with verified temperature control, power calibration, and safety interlocks. Remote setup and training options are available to facilitate seamless integration into existing lab workflows.

Designed for automated high-throughput sample preparation, the Covaris R230 is essential for laboratories aiming to optimize molecular genetics workflows and increase productivity in biomanufacturing and molecular diagnostics environments.