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Covaris M220 Ultrasonicator for Precise DNA Shearing and Sample Preparation 75 W 240V

UsedCovarisSample preparationUnited States

From€4,685.12excl. VAT

In stock

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Covaris
New/Used
Used
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Product description

Precise DNA and RNA shearing ultrasonicator with 75W power, closed vessel processing, and integrated solid state chiller.

The Covaris M220 Ultrasonicator is a high-precision DNA shearing instrument engineered for molecular biology and biotechnology workflows such as DNA/RNA fragmentation, cfDNA extraction, and cell lysis of mammalian, bacterial, and yeast cells. It features controlled, non-contact, closed vessel acoustic processing to prevent cross-contamination and preserves sample integrity with isothermal operation.

Key technical specifications include:

  • Power Output: 75 W peak incident power (PIP) for consistent nucleic acid shearing
  • Voltage Requirements: 240 V, 50-60 Hz
  • Operating Temperature: Internal control maintaining 7°C to 20°C, ambient range 19°C to 25°C, humidity 30%-70%
  • Sample Capacity: Single tube processing compatible with Covaris microTUBEs and miniTUBEs, supporting NGS sample volumes from 15 to 130 μl
  • Cooling System: Integrated solid state chiller to prevent heat-induced degradation during sonication
  • Software: Windows 10-based SonoLab 7 for precise control and reproducibility in sample preparation
  • Physical Dimensions: 14.15 kg (31.2 lbs) with shipping size approx. 51.82 cm x 36.58 cm x 36.58 cm

This ultrasonicator is widely adopted in genomics centers for optimized DNA shearing, critical in next-generation sequencing (NGS) library preparation, and widely used in molecular diagnostics and synthetic biology research. The M220 supports essential workflows in biotechnology, including gene editing and bioprocessing, by delivering reproducible fragmentation profiles without compromising nucleic acid integrity.

The unit complies with Low Voltage Directive 2006/95/EC and UL 61010-1:2004 standards, ensuring safe operation within clinical and research laboratory environments. Its compact design suits MiSeq and PGM sequencer workflows, providing critical support in biomanufacturing and molecular cloning pipelines.

Overall, the Covaris M220 is a reliable ultrasonicator specifically designed for delicate nucleic acid shearing tasks essential to advanced biomedical engineering, biotechnology process development, and precision genomic research.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 1 November 2026