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Structured illumination device improving widefield fluorescence microscopy with confocal-like optical sectioning.
The Zeiss Apotome is an advanced optical sectioning device designed to enhance widefield fluorescence microscopy by minimising out-of-focus light, thereby producing crisp, high-contrast images. By employing structured illumination, this system enables researchers to obtain confocal-like image quality without the complexity of laser scanning confocal microscopes.
Key features include:
This instrument is widely utilised in scientific fields such as cell biology, neuroscience, and biotechnology, where precise fluorescence imaging is crucial. It is commonly employed in university laboratories, biomedical research centres, and clinical environments to support a range of applications, including live-cell imaging and 3D structural analysis.
First introduced in the early 2000s, the Zeiss Apotome has undergone several advancements, with the latest iteration, Apotome 3, continuing to be a relevant and valuable tool in contemporary research settings.
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With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.
Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.
Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.
Two to six weeks, depending on refurbishment scope and whether calibration is included.
We ship to 38 countries. Crating and customs handling are quoted with the instrument.
Tell us what you need and a scientist finds it for you, usually within the hour.
Last updated 31 October 2026
