Malvern Zetasizer Nano ZS Particle Size, Zeta Potential & Molecular Size Analyzer

The Malvern Zetasizer Nano ZS is a versatile and highly accurate instrument designed for nanoparticle and molecular characterization, widely used in biotechnology, molecular diagnostics, and biopharmaceutical production pipelines. It utilizes advanced two-angle dynamic light scattering (DLS) combined with 175° non-invasive backscatter (NIBS) optics and a 532 nm laser to deliver reproducible particle size, zeta potential, and molecular weight measurements.

Key technical specifications include:

• Particle size range: 0.3 nm to 10 µm, suitable for nanoparticle and colloidal analysis in synthetic biology and bioprocessing workflows
• Zeta potential size range: 3.8 nm to 100 µm, critical in assessing surface charge for formulation stability and biomanufacturing
• Molecular weight range: 342 Da to 2×10⁷ Da, enabling molecular size determination essential in molecular cloning and protein characterization
• Repeatability: ±1%, ensuring consistent results for high-precision research applications
• Temperature range: 0°C to 90°C, adaptable for thermal stability studies in live-cell imaging sample preparations
• Sample volume: 12–500 µL for particle size, 1 mL for zeta potential measurements
• Compatibility with both disposable and reusable cuvettes, supporting various sample types and throughput demands

Equipped with Malvern Zetasizer software, the system provides comprehensive instrument control, data acquisition, and analysis tailored for complex nanoparticle characterization in biotechnology research fields, including gene editing and molecular diagnostics. The Nano ZS’s capability to measure across low and high concentration samples makes it ideal for applications in bioprocessing, nanoparticle stability assessments, and fluorescence-based biotechnology assays.

Overall, the Malvern Zetasizer Nano ZS is a critical tool for researchers seeking precise biophysical characterization of nanomaterials, proteins, and biomolecules, supporting essential workflows in synthetic biology, biomanufacturing, and clinical diagnostics.