Revvity Perkin Elmer EnVision 2105 Dual Detector Multimode Microplate Reader with AlphaScreen Laser and Stacker

The Revvity Perkin Elmer EnVision 2105 is a technologically advanced multimode microplate reader optimized for comprehensive detection modalities including absorbance, fluorescence intensity and polarization, luminescence, and AlphaScreen assays. Designed for high-throughput screening workflows in molecular biology, biotechnology, and biopharmaceutical research, it supports plate formats from 1 to 1536 wells, making it versatile for various assay scales.

Key features of this microplate reader include:

• Dual detector system with a photodiode for absorbance and dual photomultiplier tubes (PMTs) for other modes, enabling simultaneous dual-wavelength reading and improved assay flexibility
• AlphaScreen laser excitation optimized for bead-based proximity assays, critical in molecular diagnostics and protein interaction studies
• Broad detection range (230–1000 nm) with Xenon flash lamp light source and filter/mirror customization to tailor optical detection
• High sensitivity metrics: absorbance accuracy <2% at 2 OD, fluorescence detection below 4 pM fluorescein, luminescence sensitivity <75 pM ATP, and AlphaScreen detection <100 amol
• Compatibility with microplate stackers supporting 20 or 50-plate capacity for automation and increased throughput
• Integrated features include plate height sensor, Barcode readers for sample tracking, and multiple shaking modes (linear, orbital, dual orbital) for assay optimization
• Optional add-ons such as temperature control and reagent dispensers enhance assay versatility in synthetic biology, gene editing, and bioprocessing workflows

This instrument is critical in applications such as AlphaLISA / AlphaScreen proximity assays, reporter gene luminescence assays, ELISA protein quantification, and high-throughput compound screening frequently used in biotechnology, biomedical engineering, and molecular diagnostics.

The EnVision 2105 undergoes thorough service testing ensuring optical performance, mechanical reliability, and software integration, backed by a 120-day warranty in the continental US and 60 days internationally. The system includes remote setup, training support, and optional onsite installation in the New England area, ensuring seamless integration into research labs specializing in fluorescence analysis, live-cell assays, and biomanufacturing pipelines.

This microplate reader's modular design and customizable optics make it widely adopted in synthetic biology research, essential for molecular cloning workflows, and critical in biopharmaceutical production pipelines requiring sensitive, multiplexed detection modalities.

Primary keywords: multimode microplate reader, AlphaScreen laser, dual detector microplate reader, high-throughput plate reader, fluorescence and luminescence detection, biotechnology assay instrumentation Long-tail keyword phrases: widely used in molecular biology labs for AlphaScreen and fluorescence assays, essential for sensitive luminescence detection in bioprocessing, popular among synthetic biology researchers for multiplexed microplate analysis, critical for biopharmaceutical production and molecular diagnostics workflows.