Revvity Perkin Elmer EnVision 2105 Dual Detector Multimode Microplate Reader with Stacker

The Revvity Perkin Elmer EnVision 2105 is a high-throughput dual detector multimode microplate reader designed for versatile biochemical and cellular assay detection, essential in biotechnology and molecular diagnostics workflows including kinase assays, reporter gene assays, and enzyme quantification.

• Detection modes: Absorbance (ABS), Fluorescence intensity (FL), Fluorescence polarization (FP), Luminescence (LUM), and Time-resolved fluorescence (TRF).
• Optics & Light source: Xenon flash lamp excitation, photodiode for absorbance, photomultiplier tube (PMT) for fluorescence and luminescence signals with filter-based wavelength selection (230–1000 nm range).
• Plate formats supported: Compatible with microplates up to 1536 wells, including standard 96- and 384-well formats, enabling high-density screening and multiplex detection.
• Analysis modes: Supports kinetic, endpoint, and well-area scanning assays suitable for diverse quantitative and qualitative molecular biology and bioprocessing applications.
• Read times: Rapid scanning with typical read times of 22 s (96-well), 27 s (384-well), and 36 s (1536-well), enhancing throughput in drug discovery and synthetic biology research.
• Stacker integration: Automated microplate handling with stacker accommodating two stacks (20 or 50 plates) for walk-away operation, crucial for biomanufacturing and cell imaging workflows.
• Shaking options: Linear, orbital, and dual orbital shaking enhance assay reproducibility for live-cell and enzyme kinetics studies.
• Sensitivity: High sensitivity with absorbance accuracy <2% at 2 OD, fluorescence intensity detection limit <4 pM fluorescein, fluorescence polarization precision <3 mP, and luminescence sensitivity <75 pM ATP, critical for molecular diagnostics and gene editing assays.
• Software: Controlled via EnVision software (version 1.14) supporting comprehensive data analysis and assay management.
• Physical and electrical specs: Weighs 50 kg (110.2 lbs) with dimensions 42 x 55 x 58 cm; powered by 100–240 VAC, 50/60 Hz.
• Applications: Widely adopted in biotechnology fields for cellular assays, GPCR signaling evaluation, enzyme kinetics, and luminescence quantification in molecular cloning and biopharmaceutical production pipelines.

The EnVision 2105’s integrated multimode detection and automated plate handling make it indispensable for high-throughput screening (HTS), fluorescence-based assays, and luminescence analysis in clinical diagnostics and synthetic biology research. The instrument undergoes rigorous factory service including optical and mechanical system calibration, ensuring precise excitation-to-detection signal integrity without spectral bleed-through or electronic noise interference. Warranty, training, and remote setup support provide turnkey solutions for biotechnology labs seeking reliable operation.

This reader’s flexibility for assay customization, including filter and mirror module options, supports evolving bioprocessing and live-cell imaging demands, making it a critical platform for advanced molecular biology and gene editing experimentation.