Leica RM2235 Rotary Microtome for Precision Tissue Sectioning

The Leica RM2235 Rotary Microtome is engineered for high-precision tissue sectioning in histology, neuroscience, and molecular biology research. It features a low-maintenance, slack-free micrometer drive combined with vertical and horizontal specimen feed using durable cross roller bearings, ensuring reliable and reproducible section thickness control.

Key technical specifications and features include:

• Section thickness range: 1.0 to 60.0 μm, with fine increments for precise settings:
• 1.0–10.0 μm in 1.0 μm steps
• 10.0–20.0 μm in 2.0 μm steps
• 20.0–60.0 μm in 5.0 μm steps
• Specimen feed: Approx. 24 mm ± 2 mm
• Vertical stroke: 70 mm for ample sectioning length
• Maximum sectioning range without retraction: 69 mm (at 1 μm thickness)
• Maximum sectioning range with specimen retraction: 62 mm
• Adjustable specimen retraction can be manually disabled (200 μm) to aid various cutting protocols
• Equipped with dual independent handwheel locking systems enhancing operational safety
• Proprietary force balance system compensates for centrifugal forces via a pretensioned spring, providing a light and smooth handwheel action necessary for delicate bioprocessing tasks
• Compact footprint with dimensions 413 x 618 x 305 mm (WxDxH) and a working height of 168 mm at the knife blade, weighing 37 kg

The Leica RM2235 microtome is widely used in biotechnology, molecular diagnostics, and synthetic biology workflows where precise tissue sectioning is critical. It supports advanced research applications such as live-cell imaging, histopathology, and biopharmaceutical production pipelines by delivering reproducible, finely controlled sections essential for molecular cloning and gene editing sample preparations.