Leica RM2235 Manual Rotary Microtome for Controlled Paraffin Tissue Sectioning

The Leica RM2235 Manual Rotary Microtome is a precision instrument designed for controlled sectioning of paraffin-embedded tissue blocks, essential for histology, pathology, and molecular diagnostics workflows. Key features include:

• Section Thickness Range: Adjustable from 1.0 to 60.0 µm, enabling both fine sectioning and trimming steps, critical for high-quality tissue morphology analysis in biomedical research and clinical diagnostics.
• Specimen Retraction: User-selectable on/off control enhances section quality by reducing shear forces, beneficial in delicate bioprocessing and gene editing sample preparations.
• Micrometer Drive: Slack-free with cross-roller bearing guidance for smooth, repeatable specimen feed, ensuring consistent section thickness vital in synthetic biology and molecular cloning applications.
• Handwheel Operation: Dual independent locking systems with an adjustable force balance spring offset centrifugal effects, stabilizing cutting action when changing specimen clamps or weights.
• Trimming and Alignment: Knife holder base repositioning with 200 µm increments and equal trimming increments facilitate precise block facing, supporting reproducible sample preparation for fluorescence analysis and cell imaging protocols.
• Physical Specifications: Compact dimensions (24 x 20 x 12 inches), weighing 64 lbs, suitable for laboratory benchtops.
• Environmental Operating Range: Designed to perform reliably between +10°C to +35°C with up to 80% non-condensing humidity, accommodating diverse lab environments.

This microtome is widely adopted in biotechnology, enabling high-precision tissue sectioning crucial in molecular diagnostics, biomanufacturing quality control, and histopathology research. Its manual operation ensures direct tactile feedback favored by experienced researchers in neuroimaging sample preparation and live tissue analysis workflows.

Included with the Leica RM2235 is an adjustable blade holder mount and user manual, supported by a 30-day warranty, ensuring dependable performance in clinical and research laboratories requiring repeatable, high-quality tissue sections.