Leica RM2255 Motorized Rotary Microtome for Precise Tissue Sectioning

The Leica RM2255 is a high-precision motorized rotary microtome optimized for automated tissue sectioning in histology, molecular diagnostics, and bioprocessing research. Designed with a dustproof specimen feed system that features zero-backlash and maintenance-free cross roller guides, this instrument ensures reproducibility and reliability critical in synthetic biology and biomanufacturing workflows.

Key technical features include:

• Section thickness range: 0.50 to 100 µm with programmable increments (0.5 µm to 10 µm depending on range), facilitating precise microtomy for cell imaging, live-cell imaging, and fluorescence analysis applications.
• Trimming range: 1 to 600 µm with controlled increments ideal for sample preparation in molecular cloning and clinical diagnostics.
• Specimen feed: 28 mm ±1 mm via stepper motor ensures accurate specimen advance during sectioning.
• Multiple sectioning modes: Includes three motorized modes (continuous, single, step) and a manual rocking mode allowing fine control for diverse sample types.
• Electric coarse feed: Dual-speed operation at 300 µm/s and 900 µm/s enhances efficiency in biotechnological sample preparation.
• Specimen retraction: Adjustable in manual mode (5-100 µm in 5 µm steps) and variable in motorized mode, reducing sample damage during automated sectioning.
• Repositioning range: ±24 mm north-south and ±23 mm east-west of knife holder base enables versatile orientation for complex tissue geometries.
• Maximum specimen size: Accommodates samples up to 50 x 60 x 40 mm, suitable for biopsy and research specimen preparation.
• Compact footprint: Dimensions of 413 x 618 x 305 mm and 37 kg weight make it practical for laboratory benchtops.
• Centralized control panel: Ergonomically arranged with LED indicators and safety features such as a mechanically lockable handwheel and motorized coarse feed step function, ensuring precision and operator safety.

Widely used in neuroscience, cell biology, and biomedical engineering research, the Leica RM2255 supports critical biotechnological applications including gene editing and molecular diagnostics, making it an essential instrument in advanced bioprocessing and synthetic biology research environments.