Agilent BioTek EL406 96/384-Well Microplate Washer Dispenser with Ultrasonic Wash Module

The Agilent BioTek EL406 Microplate Washer Dispenser 406PUB1 is a versatile automated instrument designed for precision washing and dispensing in microplate-based assays, widely used in molecular diagnostics, biotechnology research, and biopharmaceutical production pipelines. This combined washer dispenser supports 96- and 384-well microplate formats, facilitating efficient, reproducible protocols in ELISA, cell-based assays, bead-based assays, and PCR setup applications, essential for bioprocessing and synthetic biology workflows.

_Key technical features include:_

• Dual-function peristaltic pump dispensing with volume range of 1–3000 µL per well at <10% CV precision (typical <3% CV at 1 µL).
• 96-tube Dual-Action Wash Manifold with selectable wash parameters, crosswise aspiration to minimize residue, and ultrasonic advantage for clog-free dispensing. Optional 192-tube manifold available for enhanced throughput in 384-well plates.
• Supports washing with 1 wash buffer standard; expandable to 4 buffers with an optional valve module.
• Integrated ultrasonic wash technology offers improved wash consistency and reduces contamination risk, critical for high-sensitivity fluorescence and immunoassays.
• Capability for shaking, soaking, and timed sonication to enhance reagent interaction and assay reliability.
• User-friendly interface optimized for button control preferred in clinical diagnostics and research labs.
• Compatibility with LHC software for advanced method creation and integration into automated lab environments including biomanufacturing quality control workflows.
• Compact footprint designed for space-constrained labs without compromising on functionality.

The EL406 is a reliable and cost-effective solution, ideal for laboratories involved in molecular biology, synthetic biology, and biotechnology research requiring automated liquid handling combined with microplate washing. Its robust engineering and thorough pre-shipment testing—including stress tests, volumetric accuracy validation, and ultrasonication cleaning verification—ensure high reproducibility and minimal downtime.

This model’s adaptability and precise peristaltic pumping make it critical for bioprocessing tasks such as microvolume dispensing, serial dilutions, and plate coating protocols, widely adopted in gene editing and molecular cloning workflows. Optional upgrades include syringe pump modules for 6- to 1536-well plates and integration with BioStack automated plate stackers to increase throughput.

_Supported applications:_

• Enzyme-Linked Immunosorbent Assays (ELISA)
• Meso Scale Discovery (MSD) assays
• Cell- and bead-based assays
• Magnetic and vacuum filtration protocols
• PCR setup and microvolume reagent dispensing
• Serial dilution and microplate coating

Overall, the Agilent BioTek EL406 provides a robust and validated platform for high-precision microplate washing and dispensing, making it an essential instrument in clinical diagnostics labs, biotechnological research institutes, and biomanufacturing quality control environments.