Agilent BioTek EL406 406PSUB1 Automated Microplate Washer Dispenser with Ultrasonic Advantage

The Agilent BioTek EL406 Microplate Washer Dispenser 406PSUB1 is a versatile automated laboratory instrument combining microplate washing and reagent dispensing optimized for molecular diagnostics, biotechnology research, and bioprocessing workflows. This system supports 96- and 384-well microplate formats, with upgradeability for higher density plates (6- to 1536-well), catering to diverse assay throughput demands in clinical diagnostics and synthetic biology applications.

Key technical features include:

• Dual-Action 96-Tube Manifold: Independent control of dispensing and aspiration channels ensures precise, reproducible washing suitable for ELISA, MSD assays, cell-based and bead-based assays, magnetic and vacuum filtration protocols. Optionally upgradable to a 192-tube manifold for accelerated 384-well plate washing.
• Dispensing Technology: Integrated 1 peristaltic pump and 2 syringe pumps enable accurate multi-reagent dispensing with precision <10% CV at 1 µL per well and <3% CV at 300 µL for washing.
• Ultrasonic Advantage: Built-in ultrasonic cleaning prevents clogging of wash heads and dispensers, maintaining consistent dispensing performance across extended biomanufacturing and molecular cloning workflows.
• Buffer Switching & Multiplexing: Automatic 4-buffer switching capability (with optional valve module) supports complex assay protocols requiring multiple wash buffers or reagents.
• Shaking, Soaking, and Sonication Functions: Integrated microplate shaking and soaking facilitate enhanced reagent interaction and washing efficiency for cell imaging and fluorescence-based assays.
• Software Compatibility: Supports LHC software enabling advanced method creation and seamless laboratory integration for high-throughput screening and synthetic biology research.
• Robust Build & Serviceability: Designed for reliability with comprehensive preventive maintenance including colorimetric verification of wash heads. Configurable to user needs with tested mechanical and electronic components ensuring long-term performance in biotechnology and biomedical engineering laboratories.

The EL406 is widely adopted for critical applications such as microvolume PCR setup, serial dilutions, plate coating, and bioassays where precise liquid handling is essential. Its compact footprint optimizes limited bench space while maintaining high assay reproducibility and minimizing edge effects, crucial for molecular biology research and biopharmaceutical production pipelines.

This pre-owned unit is fully serviced, stress-tested, and calibrated with gravimetric and dye-based validation protocols for consistent dispense volumes per well across multiple plate formats, delivering reliability required in molecular diagnostics and bioprocessing.

Included standard accessories:

• 96/384-well wash manifold (96-tube)
• Dual syringe pump modules
• 16-tube syringe dispense manifolds (qty 2)
• Source and waste bottles, tubing kit, vacuum pump
• Power and communication cables

Optional configurations and plate stackers are available per customer requirements.

Ideal for laboratories seeking a cost-effective, proven automated microplate washer dispenser with essential liquid handling precision for gene editing workflows, bioprocess assay automation, and live-cell assay applications in a compact, user-friendly system.

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This technical overview supports informed procurement decisions by research scientists, lab managers, and biotechnology professionals seeking reliable automated liquid handling platforms for advanced assay workflows.