Agilent BioTek EL406 Microplate Washer Dispenser 406PSUB1 with Ultrasonic and Multi-Pump Configuration

The Agilent BioTek EL406 Microplate Washer Dispenser 406PSUB1 is a versatile automated instrument designed for precise washing and dispensing in 96- and 384-well microplate formats, widely used in molecular diagnostics, cell-based assays, and biotechnology research applications. This model integrates multiple dispensing technologies including a peristaltic pump, dual syringe pumps, and an ultrasonic wash module to provide reliable and consistent liquid handling essential for ELISA, MSD assays, bead-based protocols, and PCR setup.

Key technical features include:

• Plate Format Compatibility: Supports 96- and 384-well plates, with optional syringe manifold upgrades for 6- to 1536-well plates, making it adaptable to diverse assay density requirements common in bioprocessing and synthetic biology workflows.
• Dispensing Volume Range:
• Peristaltic pump: 1–3000 µL (cassette-dependent) with <10% CV at 1 µL/well (typical <3% CV).
• 96-tube washer manifold: 50–3000 µL with <3.0% CV at 300 µL/well. Optional 192-tube manifold enables enhanced throughput for 384-well plates.
• Washing Capabilities: Customizable wash parameters with crosswise aspiration to minimize residue; features include shaking, soaking, and ultrasonic advantage to reduce clogging and maintain flow consistency.
• Dispensing Modules: Modular configuration with one reagent dispense via a peristaltic pump, two reagents via syringe pumps, and automatic 4-buffer switching ready (valve module optional), suitable for complex biopharmaceutical production pipelines and high-precision assay washing.
• Software Integration: Compatible with LHC Software for advanced method development and laboratory automation integration, supporting applications in molecular cloning workflows and clinical diagnostics.
• Physical and Operational Attributes: Ergonomic interface based on physical buttons preferred by some users, compact footprint suitable for labs with space constraints, and proven mechanical reliability validated by thorough preventive maintenance and stress testing protocols.

The EL406 model is widely regarded as a workhorse in automated microplate processing, particularly valued for its robust construction and versatility in synthetic biology research, biomanufacturing, and molecular biology labs requiring reproducible washing and dispensing accuracy.

Included accessories with the 406PSUB1 configuration:

• Standard 96/384-well wash manifold (96-tube)
• Dual syringe pump module with two 16-tube syringe dispense manifolds
• Built-in peristaltic pump
• Source and waste bottles with tubing sets
• Vacuum pump, power, and communication cables

Optional enhancements like BioStack plate stackers, valve modules for buffer switching, and syringe manifold bore options further tailor the system to specific assay demands.

This instrument undergoes comprehensive inspection, cleaning, lubrication, and electronic verification by experienced technicians, ensuring it meets stringent performance criteria before shipment. It is critical for labs in biomedical engineering, neuroscience, and biotechnology research requiring precise microvolume dispensing, fluorescence assay preparation, and high-throughput microplate washing.

The Agilent BioTek EL406 Microplate Washer Dispenser remains an essential tool for automated liquid handling workflows critical in molecular diagnostics and bioprocess optimization, providing consistent, reproducible results while reducing manual intervention in microplate-based assays.