Agilent ZAG DNA Analyzer System Unit 4 - 96-Capillary High-Throughput DNA Fragment Analyzer

The Agilent ZAG DNA Analyzer System Unit 4 is a robust capillary electrophoresis instrument designed for high-resolution, high-throughput DNA fragment and RNA analysis. Utilizing a 96-capillary array, it facilitates rapid, automated nucleic acid sizing essential in molecular biology, biotechnology, and clinical diagnostics workflows. This system supports *up to 864 samples unattended* with a maximum throughput of approximately *4,600 samples per day*, ideal for bioprocessing and molecular diagnostics applications requiring efficient sample processing.

Key specifications and features include:

• Capillary Array: Compatible with a 96-capillary format supporting high-throughput electrophoretic separations.
• Sample Handling: Accommodates *nine 96-well PCR microplate trays* for markers and samples, with additional holders for deep-well plates used for buffer and waste.
• Minimum Sample Volume: 20 µL per injection ensures low sample consumption while maintaining sensitivity.
• Separation Throughput: 96 samples are processed within approximately 20 minutes, enabling rapid data generation for gene editing and synthetic biology projects.
• Sizing Range: Detects DNA fragments from 35 base pairs (bp) up to 20,000 bp, adaptable via different DNA analysis kits suitable for microsatellite or restriction digest analysis.
• Sizing Accuracy and Resolution: Typical sizing accuracy is 5% or better, with resolution as fine as 3 bp depending on gel conditions, critical for precise DNA fragment analysis in molecular cloning workflows.
• Detection Sensitivity: As low as 5 pg/µL for DNA fragments, providing reliable detection for low-abundance nucleic acid samples.
• Software & Control: Comes equipped with ProSize data analysis software and ZAG DNA Analyzer controller software for data acquisition and in-depth fragment size quantitation.
• Consumable Lifespan: The 96-capillary cartridge is consumable with a one-year or 1000 injection lifespan, ensuring consistent performance in biomanufacturing quality control assays.

This compact instrument integrates efficiently into laboratory benchtops, suitable for research environments focused on molecular genetics, biotechnology innovation, and biomedical engineering. Its automated, high-throughput operation reduces manual intervention, increasing laboratory efficiency and reproducibility—key for large-scale sequencing validation and molecular diagnostics studies.

Applications:

• DNA fragment sizing and quantitation for PCR fragments
• Microsatellite analysis in genetic research
• Restriction digest fragment analysis for cloning and synthetic biology studies

Additional Benefits:

• Comes with a comprehensive set of accessories, including sample holders, waste bottles, and communication cables.
• Fully serviced and tested to ensure stable power supply, fluidics, optical alignment, and software communication reliability.
• Warranty coverage supports parts and labor, with options for remote setup and training, beneficial for university labs and biopharma research facilities.
• Supports sustainability goals by offering a pre-owned solution with verified performance aligned to environmental responsibility.

This Agilent ZAG DNA Analyzer System is widely adopted in biotechnology research for molecular cloning workflows, gene editing validation, and biopharmaceutical production pipelines, delivering precise DNA sizing data that facilitates advanced molecular diagnostics and synthetic biology applications.