Molecular Devices ImageXpress Micro 4 Automated High Content Imaging System with sCMOS Camera

The Molecular Devices ImageXpress Micro 4 High Content Imaging System is an advanced automated microscopy platform designed for high-throughput imaging of multiwell plates (up to 1536 wells) and microscope slides, widely used in molecular diagnostics, bioprocessing, and synthetic biology research workflows.

Key technical features include:

• Imaging hardware:
• High-sensitivity *Andor Zyla sCMOS camera* delivering a 1.97 mm² field of view at 10x magnification for rapid image acquisition (>200,000 wells/day throughput)
• Motorized 4-position objective changer with Nikon Plan APO objectives (4x/0.20, 10x/0.45, 20x/0.75, 40x/0.95) supporting diverse magnification needs for detailed cellular and subcellular imaging
• 5-position motorized filter changer with emission filters for DAPI, FITC, TRITC, and CY5 dyes enabling multicolor fluorescence experiments essential for multiplexed assays
• Laser and image-based autofocus ensures precise XY stage positioning and Z-axis focus stability critical for quantitative fluorescence analysis and 3D imaging

• Automation & compatibility:
• Supports multiwell plate formats up to 1536 wells and slides with adapters, facilitating phenotypic screening, cell viability assays, and assay workflows in biomanufacturing pipelines
• Robotics and laboratory automation compatibility for integration into high-throughput screening workflows and synthetic biology research environments

• Software capabilities:
• Comes with MetaXpress 6.7 Acquisition and Offline Analysis Software including time-series acquisition, Z-series capture and analysis, asynchronous kinetics, and custom module editing for tailored assay development
• Supports basic 3D imaging through Z-stacks and 2D projections, valuable in cell migration, 3D spheroid, and organoid analysis applications

• Illumination:
• Stable Lumencor Sola LED light engine provides uniform excitation with consistent power and wavelength stability, crucial for reproducible fluorescence signal intensity in molecular diagnostics
• Widefield fluorescence and brightfield imaging modes adaptable for diverse assay types in biotechnology and biomedical engineering

This system is fully tested and serviced, ensuring optimal optical clarity, precise filter operation, and reliable mechanical stage movement across all axes for artifact-free high-content imaging. It is supported by a warranty and optional remote setup and training, making it well-suited for deployment in molecular biology research labs focusing on gene editing, synthetic biology, and biopharmaceutical development.

Long-tail biotechnology keywords naturally integrated:

*High-throughput multicolor fluorescence microscopy for molecular cloning workflows*, *critical in biopharmaceutical production pipelines*, *widely adopted in phenotypic screening and live-cell imaging in synthetic biology studies*, *essential for 3D spheroid and organoid analysis in biomedical engineering*.

This pre-owned system includes all necessary accessories such as power supply, software licenses with dongles, computer workstation, and communication cables, ensuring readiness for immediate integration into biotechnology and clinical diagnostics laboratories.