Bruker Avance III/400

Bruker Avance III/400 is a high-performance 400 MHz nuclear magnetic resonance (NMR) spectrometer designed for detailed molecular structure analysis. This instrument is essential for researchers requiring precise characterisation of complex compounds across various scientific disciplines.

Key features include:

• Versatile Probe Options: Equipped with multiple probes, including the 5 mm BBFO SmartProbe, facilitating the observation of a wide range of nuclei such as ¹H, ¹³C, ¹⁵N, ¹⁹F, and ³¹P.

• Advanced Experimentation: Capable of conducting modern liquid-phase NMR experiments, including state-of-the-art two- and three-dimensional techniques with pulsed field gradients.

• Temperature Control: Offers a variable temperature range from -150°C to +150°C, enabling studies under diverse thermal conditions.

• High Sensitivity: Delivers exceptional signal-to-noise ratios, enhancing the detection of subtle spectral features.

• Automation Capabilities: Features the SampleXpress autosampler for efficient, high-throughput sample analysis.

This spectrometer is widely utilised in fields such as biotechnology, molecular biology, organic chemistry, and pharmaceutical research. Its applications are critical in bioprocessing, gene editing, synthetic biology, and molecular diagnostics, making it indispensable for tasks like protein structure elucidation, metabolomics, and drug discovery.

Commonly found in university laboratories, biomedical research centres, and pharmaceutical companies, the Bruker Avance III/400 has been a cornerstone in scientific research since its release in the early 2010s. As of December 2024, Bruker has scheduled the end of service for this model, reflecting its longstanding contribution to the scientific community.