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Molecular Devices SpectraMax M3 Multimode Microplate Reader with Tunable Monochromators

UsedMolecular DevicesMicroplate readersUnited States

Price on request

In stock

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Robotic-compatible
Yes
Plate formats
6, 12, 24, 48, 96, 384 wells
Light source
Xenon Flash Lamp (1 joule/flash)
Detectors
2 photomultiplier tubes (PMT)
Shaker time
0 to 999 seconds
All 32 specifications
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Specifications 32

Brands
Molecular Devices
New/Used
Used
Robotic-compatible
Yes
Plate formats
6, 12, 24, 48, 96, 384 wells
Light source
Xenon Flash Lamp (1 joule/flash)
Detectors
2 photomultiplier tubes (PMT)
Shaker time
0 to 999 seconds
Temp. control
2°C above ambient to 60°C
Temp. uniformity
< 1°C at 37°C set point
Temp. accuracy
±1°C at 37°C set point
Readings
Endpoint, Kinetic Spectral Scanning
Standard Read Times (minutes:seconds)* 96 wells 384 wells
Absorbance 0:18 0:49 Fluorescence Intensity 0:17 0:48 Luminescence 2:00 7:00
Wavelength range
200–1000 nm
Wavelength selection
Monochromator, tunable in 1.0 nm increments
Wavelength bandwidth
4.0 nm
Wavelength accuracy
±2.0 nm
Wavelength repeatability
±0.2 nm
Photometric range
0–4.0 OD
Photometric resolution
0.001 OD
Photometric accuracy
(microplate) < ±0.006 OD ±1.0%, 0–2 OD (cuvette) < ±0.005 OD ±1.0%, 0–2 OD
Photometric precision
< ±0.003 OD ±1.0%, 0–2 OD
Stray light
< 0.05% @ 230 nm
Fluorescence Intensity Performance
Top or bottom
Bandwidth (EX, EM)
9 nm, 15 nm
Optimized sensitivity
? 1 pM fluorescein in 96 wells, ? 1.5pM in 384 wells
Guaranteed sensitivity
< 5 pM fluorescein in 96 wells or cuvette < 20 pM in 384 wells
Luminescence Performance
Top or Bottom
Dynamic range
> 6 decades
Cross-talk
< 0.3% in white 96- and 384-well Microplates
Dimensions
23 x 16 x 9 inches
Weight
36 lbs
Power
< 420 watts, 100–240 VAC, 3.5 A, 50/60Hz

Product description

High-performance multimode microplate reader with tunable monochromators for absorbance, fluorescence, and luminescence assays.

The Molecular Devices SpectraMax M3 is a versatile multimode microplate reader designed for diverse biochemical and cell-based assay formats in biotechnology, molecular diagnostics, and bioprocessing workflows. It supports absorbance, fluorescence intensity, and luminescence measurements on a single platform, facilitating seamless integration into molecular biology and synthetic biology research pipelines.

  • Tunable monochromators with 1 nm wavelength increments provide precise spectral optimization over a broad range:
  • Absorbance: 200–1000 nm
  • Fluorescence and Luminescence: 250–850 nm
  • Equipped with dual photomultiplier tube (PMT) detectors to deliver high sensitivity and dynamic range critical for low-concentration biomolecule detection.
  • Compatible with multiple plate formats (6–384 wells) and cuvettes, enhancing flexibility for various throughput needs in biomanufacturing and gene editing assay development.
  • Features both top and bottom reading modes, optimizing detection sensitivity for suspension and adherent cell assays, essential for live-cell imaging and cell-based fluorescence analysis.
  • Robust temperature control from 2°C above ambient to 60°C with <1°C uniformity ensures stable assay conditions, supporting sensitive enzyme kinetics and cell culture studies.
  • Fast read times (e.g., ~18 seconds for absorbance in 96-well plates) and 100+ integrated protocols accelerate experimental workflows in molecular cloning and clinical diagnostics.
  • Robotic compatibility allows automation integration, suitable for high-throughput biopharmaceutical production and screening applications.

This reader is engineered for reliability and precision, meeting the stringent needs of biotechnology research and clinical laboratories. The SpectraMax M3’s combination of tunable detection, flexible assay accommodation, and validated performance makes it widely adopted in molecular diagnostics and essential for workflows involving fluorescence-based assays and luminescence measurements.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Yes. Every verified supplier states which service partners cover the instrument, and we list that alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 19 October 2026