Revvity Perkin Elmer EnVision 2105 Dual Detector Multimode Microplate Reader with AlphaScreen Laser and Stacker

The Revvity Perkin Elmer EnVision 2105 is a dual detector multimode microplate reader designed for high-throughput biochemical and cell-based assays widely adopted in biotechnology and molecular diagnostics research. This instrument integrates an AlphaScreen laser for bead-based proximity assays alongside absorbance, fluorescence, fluorescence polarization, and luminescence detection modes supporting 1- to 1536-well microplates including 96- and 384-well formats.

Key features include:

• Detection modes: Absorbance (0–4 OD with <2% accuracy), fluorescence intensity (sensitivity <4 pM fluorescein), fluorescence polarization (<3 mP), luminescence (<75 pM ATP), and AlphaScreen (<100 amol in 384 well plates).
• Dual detection system: Photodiode for absorbance and dual photomultiplier tubes (PMT) for other modes allow simultaneous dual wavelength readings and top/bottom measurements essential for multiplexed biotechnology assays.
• Light sources: Xenon flash lamp and AlphaScreen laser enable excitation across a 230–1000 nm range depending on installed filters.
• Microplate handling: Includes a microplate stacker with configurable stacks (20 or 50 plates), plate height sensors, and barcode readers to streamline high-throughput workflows.
• Shaking modes: Linear, orbital, and dual orbital shaking optimize assay mixing critical in live-cell and biochemical assay fidelity.
• Optical customization: Supports interchangeable mirror modules and excitation/emission filters enabling tailored assay configurations from molecular cloning workflows to synthetic biology research.

The EnVision 2105 is critical for applications such as:

• AlphaScreen and AlphaLISA proximity assays widely used in drug discovery and bioprocessing
• Reporter gene luminescence assays essential for gene editing validation
• ELISA protein quantitation and absorbance-based enzymatic assays
• Fluorescence intensity and polarization measurements for receptor binding and cell imaging studies
• High-throughput compound screening to accelerate biopharmaceutical production pipelines

Fully serviced with preventive maintenance and validated for all optical and mechanical functions, this system guarantees reliable performance for demanding biotechnology labs. The included desktop PC runs the EnVision application for seamless data acquisition and analysis. Comprehensive warranty, remote training, and technical sales consultation are offered to support integration into molecular diagnostics and biomedical engineering workflows.

This multimode microplate reader is a versatile, high-performance instrument offering robust optical sensitivity and throughput necessary for advanced biotechnology and clinical diagnostics research environments.