LI-COR Biosciences Odyssey Imaging System

The LI-COR Odyssey® Infrared Imaging System revolutionised protein analysis by introducing near-infrared (NIR) fluorescence detection, offering a superior alternative to traditional chemiluminescence methods. This system enables precise, quantitative imaging of Western blots, protein arrays, and nucleic acid gels, delivering clear, sharp bands with minimal background noise.

Key features include:

• Wide Linear Dynamic Range: Accurately detects both strong and weak signals on the same blot, enhancing quantification accuracy.
• High Sensitivity: NIR fluorescence reduces autofluorescence and light scatter, resulting in cleaner backgrounds and higher signal-to-noise ratios.
• Dual-Channel Detection: Simultaneously visualises and quantifies two separate targets, facilitating multiplex analysis.
• Direct Detection: Eliminates the need for film, darkrooms, or substrates; fluorescent signals remain stable on membranes for extended periods.
• Versatile Applications: Supports a range of assays, including Coomassie-stained gels, DNA gel staining, ELISA/FLISA, EMSA, glycoprotein detection, In-Cell Western™ assays, Northern and Southern blots, protein arrays, and tissue section imaging.

Widely adopted in molecular biology, biochemistry, and proteomics, this imaging system is utilised in university laboratories, biomedical research centres, and clinical environments. Since its release in 2001, the Odyssey has set a new standard in quantitative imaging, with its technology continuing to evolve to meet the demands of modern research.