Lonza Penicillin-Streptomycin

Lonza's Penicillin-Streptomycin Solution (Cat. No. 44631) is a vital antibiotic mixture designed to prevent bacterial contamination in mammalian cell cultures. This solution combines penicillin G, effective against Gram-positive bacteria, and streptomycin, targeting Gram-negative bacteria, ensuring comprehensive protection during cell culture applications.

Key features include:

• Broad-spectrum efficacy: Combats both Gram-positive and Gram-negative bacterial contaminants.
• High potency: Each millilitre contains 5,000 units of penicillin and 5,000 micrograms of streptomycin.
• Cell culture compatibility: Formulated to be non-toxic to mammalian cells, preserving cell viability and function.
• Convenient concentration: Provided as a 100x concentrate, facilitating easy dilution to the recommended working concentration of 100 units of penicillin and 100 micrograms of streptomycin per millilitre of culture media.
• Manufactured under cGMP regulations: Ensures consistent quality and reliability for research applications.

This antibiotic solution is indispensable in various scientific fields, including molecular biology, biotechnology, and pharmaceutical research, where maintaining sterile cell cultures is paramount. It is widely utilised in university laboratories, biomedical research centres, and pharmaceutical companies to safeguard cell cultures from bacterial contamination.

First introduced in 1955, penicillin-streptomycin solutions have remained a cornerstone in cell culture practices, underscoring their enduring relevance in contemporary research settings.