GE Wave Bioreactor 2050EHT with Integrated Wavepod II Controller for Controlled Cell Culture

The GE Wave Bioreactor 2050EHT is a versatile benchtop rocking bioreactor designed for advanced bioprocessing and mammalian cell culture applications such as CHO cell expansion, protein production, and vaccination manufacturing. Its modular design allows scalability from small to large-volume bioreaction setups.

• Rocking Platform: Accommodates single-use cell culture bags up to 50L volume, with adjustable rocking angles from 2° to 12° and rocking rates of 2 to 40 rocks per minute to optimize shear stress and mixing conditions critical for sensitive cells.
• Temperature Control: Maintains culture temperature within 10°C to 50°C, supporting a wide range of cell types and experimental protocols.
• Integrated Control Modules:
• The Wavepod II controller integrates precise gas mixing for CO2 (0-15% control) and O2 (0-50% control), as well as dissolved oxygen (DO) and pH monitoring and control—essential parameters for maintaining physiological conditions in cell cultures.
• The controller supports dissolved oxygen measurement range from 0% to 250% air saturation and pH control within 6 to 8, critical for bioprocess optimization and molecular diagnostics workflows.
• Air and Gas Handling: Operates at air pressure of 3 psi (0.2 bar) with inlet pressures for CO2 and O2 between 0.7 to 1.0 bar, enabling precise atmospheric control in bioprocessing and synthetic biology applications.
• User Interface: Features an intuitive, bright touch-screen control panel for setting and monitoring temperature, rocking speed, angle, and air mixing parameters in real-time, facilitating reproducibility and ease of use.
• Connectivity and Automation: Optional Converter 100 interface provides Ethernet and serial communication optimized for integration with UNICORN DAQ software, allowing automated data acquisition and process control, important for biomanufacturing and cell therapy process development.
• Dimensions & Power: Compact footprint (40x44x28 inches), weighing 108 lbs, powered by standard 100-120V, 50/60 Hz electrical supply consuming 630VA.

This system is widely used in biotechnology and biomedical engineering research environments for live-cell imaging studies, protein expression optimization, and vaccine production. Its sophisticated control of gas mixtures, pH, and DO makes it critical in biopharmaceutical production pipelines and cell-based assay development. The Wave Bioreactor 2050EHT is particularly valued for its gentle rocking motion, which preserves cell viability in gene editing and synthetic biology experiments, supporting robust and scalable cell culture workflows.

Keywords: rocking bioreactor system, benchtop bioreactor, single-use bag bioreactor, cell culture bioreactor, mammalian cell culturing, bioprocessing controller, gas mixing bioreactor, biotechnology research equipment, biopharmaceutical production, molecular diagnostics bioreactor.