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Rat IgG2b κ antibody targeting CD11b; fluorochrome-conjugated for flow cytometry; blocks adhesion and C3bi binding.
The BD Biosciences M1/70 monoclonal antibody is a rat-derived IgG2b κ antibody specifically targeting CD11b, also known as Integrin alpha M (Itgam or αM). This 170-kDa type 1 transmembrane glycoprotein is a component of the heterodimeric Mac-1 integrin (CD11b/CD18, αMβ2), also referred to as complement receptor 3 (CR3). Mac-1 plays a crucial role in mediating adhesion to ICAM-1 (CD54), ICAM-2 (CD102), fibrinogen, and binding to C3bi.
Key features of this antibody include:
This antibody is widely used in immunology, cell biology, and biotechnology research, particularly in studies involving granulocytes, macrophages, dendritic cells, natural killer cells, microglia, and B-1 B lymphocytes. Its applications are prevalent in university laboratories, biomedical research centres, and clinical research institutions. The M1/70 clone has been a staple in research since its development and continues to be relevant in current scientific investigations.
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With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.
Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.
Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.
Two to six weeks, depending on refurbishment scope and whether calibration is included.
We ship to 38 countries. Crating and customs handling are quoted with the instrument.
Tell us what you need and a scientist finds it for you, usually within the hour.
Last updated 5 November 2026
