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Thermo Fisher Scientific Orbitrap Lumos

UsedThermo Fisher ScientificAnalytical devices - otherNetherlands
Procurable

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Mass Range
m/z 50–2,000 or 200–4,000 or up to 6,000 without precursor ion selection
Resolution
up to 1,000,000 FWHM at m/z 200
Acquisition Rate (Orbitrap)
up to 30 Hz
Acquisition Rate (Linear Ion Trap)
up to 40 Hz
Mass Accuracy (External Calibration)
<3 ppm RMS
Availability
Procurable
Lead time
Confirmed with your quote
All 19 specifications
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Specifications 19

Brands
Thermo Fisher Scientific
New/Used
Used
Dimensions
1,524 x 1,270 x 1,473 mm
Weight
179 kg
Mass Range
m/z 50–2,000 or 200–4,000 or up to 6,000 without precursor ion selection
Resolution
up to 1,000,000 FWHM at m/z 200
Acquisition Rate (Orbitrap)
up to 30 Hz
Acquisition Rate (Linear Ion Trap)
up to 40 Hz
Mass Accuracy (External Calibration)
<3 ppm RMS
Mass Accuracy (Internal Calibration)
<1 ppm RMS
Dynamic Range
>5,000 within a single OTMS spectrum
Polarity Switching Time
<1.1 sec
Vacuum System
Split-flow turbomolecular pump controlling vacuum in three regions; Aluminum high-vacuum analyzer chambers; Advanced Vacuum Technology reducing the pressure in the ultra-high vacuum region to <2 × 10⁻¹⁰ Torr
Ionization Methods
APCI, ESI, HESI, Nanospray
Ion Source
Adjustable heated electrospray ionization (HESI) probe
Advanced Features
Advanced Active Beam Guide, Advanced Quadrupole Technology, Advanced Vacuum Technology, ETD HD, UVPD
Software Compatibility
Xcalibur™, Tune, Proteome Discoverer™, ProSight™, TraceFinder™, Mass Frontier™, Compound Discoverer™
Availability
Procurable
Lead time
Confirmed with your quote

Product description

High-resolution tribrid mass spectrometer integrating quadrupole, ion trap, and Orbitrap analyzers for advanced biomolecular analysis.

The Orbitrap Fusion Lumos is a state-of-the-art Tribrid mass spectrometer that integrates quadrupole, ion trap, and Orbitrap mass analysers into a single, versatile platform. This configuration enables comprehensive analysis of complex biological samples, making it indispensable in proteomics, metabolomics, and biotechnology research.

Key features include:

  • High-resolution mass spectrometry: Achieves up to 500,000 FWHM at m/z 200, facilitating precise mass determination.
  • Multiple fragmentation techniques: Supports Collision-Induced Dissociation (CID), Higher-Energy Collisional Dissociation (HCD), and Electron Transfer Dissociation (ETD), enhancing structural elucidation of biomolecules.
  • Synchronous Precursor Selection (SPS): Improves quantification accuracy in multiplexed experiments by reducing precursor co-isolation effects.
  • Advanced Peak Detection (APD): Enhances peptide and protein identification from minimal sample amounts, crucial for low-abundance analytes.

This instrument is widely applied in post-translational modification (PTM) studies, lipidomics, and biopharmaceutical development, offering unparalleled sensitivity and specificity. Its capabilities are particularly beneficial in biotechnology, where precise molecular characterisation is essential for bioprocessing, gene editing, and synthetic biology applications.

Commonly utilised in university laboratories, biomedical research centres, and clinical environments, the Orbitrap Fusion Lumos has been a cornerstone in mass spectrometry since its release in 2013, with ongoing relevance in cutting-edge research.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 22 October 2026