Nova Biomedical BioProfile FLEX2 Multi-Module Automated Cell Culture Analyzer with Osmometer and Gas, Cell Viability Modules

The Nova Biomedical BioProfile FLEX2 Automated Cell Culture Analyzer combines advanced biochemical and biophysical testing modules into one integrated platform designed for cell culture monitoring and bioprocessing applications. Equipped with chemistry, gas, osmolality (OSM48 osmometer), and cell density/viability modules, the system supports fast, automated analysis essential for molecular diagnostics, biopharmaceutical production pipelines, and synthetic biology research.

• Modules Included:
• Chemistry Module: 11 tests including glucose, lactate, glutamine, glutamate, ammonia, sodium (Na⁺), potassium (K⁺), and calcium (Ca²⁺)
• Gas Module: pH, partial pressure of CO₂ (pCO₂), and partial pressure of O₂ (pO₂)
• Osmolality Module: Measures osmolality quickly using integrated OSM48 osmometer (240 sec/sample)
• Cell Density & Viability Module: Quantifies cell diameter (4–70 μm), density (100,000–80,000,000 cells/mL), and viability for live-cell monitoring

• Sample Handling:
• Automated sampling from 96-well microplates, syringes, or a 24-position external load-and-go sample tray
• Minimal sample volumes required (e.g., chemistry module: 135 µL, gas module: 275 µL) with rapid turnaround times (as fast as 120 seconds per test)

• Technology Features:
• Maintenance-free single-use microsensor cards reduce downtime and frequent calibrations
• Cartridge-based reagent management system (RMS) simplifies consumables handling
• Walk-away automation supports high-throughput workflows with up to 24 samples per run
• Compact benchtop dimensions (43 x 64 x 61 cm) and moderate weight (42.6 kg) facilitate laboratory integration

• Applications:
• Monitoring nutrient consumption and metabolite production in cell culture and bioprocess development
• Quality control and in-process monitoring for biomanufacturing and biopharmaceutical production
• Optimization of media formulations, feeding strategies, and scale-up processes
• Critical support for molecular cloning workflows and synthetic biology research requiring precise cell health assessment

The BioProfile FLEX2 system is widely adopted for its combined capability to perform essential metabolic, gas, osmotic, and viability analyses in a single automated instrument, thus enhancing productivity and process control in biotechnology and clinical diagnostics laboratories.

This pre-owned unit has been fully serviced, tested, and calibrated by experienced technicians, ensuring reliable performance. Remote setup and training options are available to facilitate integration into your research or manufacturing environment.

Keywords: automated cell culture analyzer, multi-module biochemical analyzer, cell density and viability analysis, osmometer, gas and pH analyzer, biopharmaceutical production monitoring, molecular diagnostics, synthetic biology research, biotech bioprocessing, cell culture metabolic profiling, low volume biochemical testing, inline bioprocess analytics