Nova Biomedical BioProfile FLEX2 Automated Cell Culture Analyzer with Chemistry, Gas, and Osmometry Modules

The Nova Biomedical BioProfile FLEX2 Automated Cell Culture Analyzer is a versatile instrument designed for automated, high-throughput biochemical analysis of cell culture and bioprocess samples. It integrates chemistry, gas, and osmolality testing modules to provide comprehensive monitoring of cell health and metabolic parameters essential in biotechnology and biopharmaceutical manufacturing workflows.

• Multi-modular configuration: Includes Chemistry Module (11 tests with maintenance-free sensor card technology), Gas Module (pH, PCO2, PO2), and OSM48 Osmometer Module for osmolality measurements.
• Sample handling: Automated sampling compatible with 96-well plates, syringes, and a 24-position load-and-go tray, supporting seamless integration with upstream bioprocess and cell culture systems.
• Analytical performance:
• Chemistry tests: Glucose, Lactate, Glutamine, Glucose, Ammonium, Sodium, Potassium, Calcium; completed in 120 seconds using 135 µL sample.
• Osmolality: Completed in 240 seconds with 140 µL sample.
• Gas panel: pH, PCO2, PO2; results in 120 seconds with 275 µL sample.
• Combined analysis time: 270 seconds from 275 µL sample when all modules run concurrently.
• Technology advantages:
• Cartridge-based reagent management system (RMS) with single-use microsensor cards minimizes calibration needs and maintenance.
• Automated walk-away throughput allows up to 24 samples in queue, enhancing laboratory efficiency.
• Physical specifications: Dimensions 43 x 64 x 61 cm; weight 42.6 kg.
• Optional modules: Cell Density and Viability Module available for enhanced cell culture process monitoring.
• Applications:
• Essential for monitoring nutrient consumption and metabolite production during cell culture processes.
• Widely used in bioprocessing, biopharmaceutical production pipelines, and process development.
• Critical for upstream manufacturing quality control and optimization of media formulation.
• Supports scale-up studies and process troubleshooting in both research and industrial biotechnology settings.

This analyzer is widely adopted among molecular biology researchers and bioprocess engineers for its precise measurement capabilities, critical in molecular diagnostics, synthetic biology research, and biomanufacturing process monitoring. The integrated modules provide rapid and reliable data, enabling informed decision-making in live-cell imaging and fluorescence analysis workflows as part of broader cell health assessments.

The BioProfile FLEX2 comes fully serviced, with warranty coverage and options for remote setup, operation training, and technical consultation, ensuring swift integration into laboratory or manufacturing environments. It is designed to support efficient, high-throughput sample analysis, making it a valuable asset for laboratories engaged in advanced cell culture analysis and clinical diagnostics.

Keywords: Automated Cell Culture Analyzer, chemistry testing, blood gas analysis, osmolality measurement, bioprocess monitoring, molecular diagnostics, synthetic biology, biomanufacturing, cell viability, biopharmaceutical manufacturing.