SPT Labtech Mosquito HV Liquid Handler for Precise Low-Volume Automated Pipetting

The SPT Labtech Mosquito HV Liquid Handler is a specialized automated liquid handling system designed for ultra-precise, low-volume pipetting in molecular biology and biotechnology workflows. Featuring 16 fixed positive displacement channels, it accurately dispenses volumes ranging from 500 nL to 5 µL into SBS format microplates (96, 384, and 1,536 wells), supporting applications such as assay miniaturization, PCR setup, serial dilutions, and compound dispensing.

Key technical specifications include:

• 5-position deck compatible with multiple plate formats for flexible assay configurations
• High-throughput capability: ~2 minutes per 96-well plate, 3 minutes per 384-well copy, and 5 minutes for 4x384 plate stamping
• Exceptional precision and accuracy with less than 3% error and CV across the entire volume range, essential for quantitative molecular diagnostics and bioprocessing
• Supports a broad range of liquid types, including viscous and low-tension samples, facilitated by disposable pipette tips to eliminate sample carry-over
• Integrated active humidity control chamber sustaining 10–85% relative humidity to maintain sample integrity during miniaturized dispensing
• Compact footprint (790 mm x 470 mm x 690 mm) and lightweight (27 kg), suitable for benchtop laboratory environments

The Mosquito HV is widely adopted in synthetic biology research and biopharmaceutical production pipelines where accuracy in nanoliter to microliter liquid handling is critical. Its positive displacement pipetting mechanism ensures reproducible transfers in gene editing workflows, molecular cloning, and high-density screening assays. The instrument's software enables comprehensive method setup, plate mapping, and run execution, promoting operational efficiency in complex biomanufacturing processes.

Accessories include an active humidity chamber and spool cover. Consumables such as pipette spools are separately required. The system is delivered with power and communication cables and pre-installed Mosquito control software. Rigorous factory testing confirms functional diagnostics, plate alignment accuracy, and pipetting precision, assuring reliability for clinical diagnostics and biotechnology research laboratories.

This model, manufactured in 2020, comes fully serviced and warranted, and is supported with after-sales technical consultation and installation options. The Mosquito HV Liquid Handler aligns with the needs of laboratories engaged in molecular diagnostics, live-cell assay preparation, and high-throughput fluorescence analysis, making it an essential tool for enhancing reproducibility and cost-effectiveness in miniaturized liquid transfer workflows.