Revvity Perkin Elmer EnVision 2105 Dual Detector Multimode Microplate Reader with TRF Laser

The Revvity Perkin Elmer EnVision 2105-0020 is a high-throughput dual detector multimode microplate reader designed for advanced life science research applications, including biotechnology, molecular diagnostics, and drug discovery workflows. Equipped with both a photodiode for absorbance and a photomultiplier tube (PMT) for fluorescence, luminescence, and fluorescence polarization detection, it enables simultaneous dual wavelength measurements for enhanced assay versatility.

Key technical features include:

• Detection modes: Absorbance, Luminescence, Fluorescence intensity, Fluorescence Polarization (FP), and Time-Resolved Fluorescence (TRF) utilizing filter- and mirror-dependent wavelength selection spanning 230–1000 nm.
• Light sources: Xenon flash lamp and an integrated time-resolved fluorescence (TRF) laser for enhanced sensitivity in TRF assays critical for molecular diagnostics and bioprocessing.
• Sensitivity specifications:
• Absorbance range 0–4 OD with <2% accuracy at 2 OD.
• Fluorescence detection sensitivity <4 pM fluorescein equivalent for 96-well plates.
• TRF sensitivity <55 fM europium (Eu) with <11 amol/well.
• Luminescence detection sensitivity <75 pM ATP equivalent.
• Plate formats supported: 1- to 1536-well plates including standard 96 and 384-well microplates, enabling scalability for biomanufacturing assay development.
• Mechanical capabilities: Linear, orbital, and dual orbital shaking modes facilitate robust cell-based assay workflows.
• Additional instrumentation: Includes plate height sensor, PlateID barcode readers, and optical modules customizable with various filter and mirror options to optimize assay parameters.

This instrument is widely used in high-throughput drug discovery screening, enzyme kinetics, reporter gene assays, protein interaction studies, and synthetic biology research. Its integrated TRF laser and multimode detection make it an essential tool for fluorescence analysis and time-resolved assays in molecular biology and biopharmaceutical production pipelines.

The EnVision 2105-0020 comes with a desktop PC preloaded with the EnVision control software, remote setup, and technical training options. It is thoroughly serviced, tested for all optical and mechanical components, and backed by a warranty, ensuring reliable data acquisition and system integration.

This microplate reader supports critical biotechnological applications such as live-cell imaging assays, gene editing validation, molecular cloning workflows, and synthetic biology experiments, making it a versatile platform for academic and industrial life science laboratories.

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Keywords: multimode microplate reader, TRF laser microplate reader, dual detector microplate reader, fluorescence polarization, high-throughput screening, molecular diagnostics instrument, bioprocessing assay reader, absorbance luminescence detection, biotechnology research equipment, time-resolved fluorescence assays, synthetic biology instrumentation, cell-based screening microplate reader.