Thermo Fisher Scientific NanoDrop 3300 Microvolume Fluorometer for Nucleic Acid and Protein Quantification

The Thermo Fisher Scientific NanoDrop 3300 Fluorometer is a compact, USB-powered microvolume fluorescent spectrometer optimized for sensitive quantification of nucleic acids (DNA/RNA) and proteins using sample volumes as low as 1 µL. Utilizing light-emitting diode (LED) excitation at UV (265 nm), blue (470 nm), and broadband white (460–650 nm) wavelengths, it enables versatile applications including RiboGreen, PicoGreen, GFP fluorescence assays, as well as advanced FRET and nanoparticle spectral analysis.

Key technical features include:

• High-sensitivity detection via a 2048-element linear silicon CCD array for spectral and quantitative fluorescence data acquisition.
• Wavelength accuracy of ±1 nm across a 400–750 nm emission range, facilitating precise fluorescence characterization.
• Minimal sample consumption, critical for maintaining valuable sample material in molecular diagnostics, bioprocessing, and synthetic biology workflows.
• Direct sample pipetting onto the optical measurement surface enables rapid, clean, and reproducible measurements with wipe-clean convenience.
• USB connectivity ensures easy integration with Windows 10 PC software for data analysis and instrument control.
• Compact footprint (6 × 8 × 4 inches) and lightweight design (5 lbs) allow seamless benchtop placement in facilities focused on biotechnology research, clinical diagnostics, and biomanufacturing.

This fluorometer is widely used in applications requiring precise fluorescence quantification including gene editing validation, biopharmaceutical production pipelines, and live-cell imaging assay development. Its broad excitation range and spectral detection capabilities make it a valuable instrument for researchers demanding reliable, rapid, and low-volume fluorescence measurements in advanced biotechnological and biomedical engineering settings.