SPT Labtech Mosquito HV Automated Liquid Handler with 16-Channel Positive Displacement Pipetting

The SPT Labtech Mosquito HV Liquid Handler is a precision automated liquid handling workstation designed for efficient, low-volume pipetting in biotechnology and molecular biology research. It features a 16-channel positive displacement pipetting head with a flexible volume range of 500 nL to 5 µL, supporting protocol miniaturization essential for cost-effective assay development in synthetic biology, gene editing, and molecular diagnostics workflows.

Key technical specifications include:

• Deck Configuration: 5 plate positions compatible with SBS-format microplates in 96-, 384-, and 1,536-well formats, enabling versatile high-throughput applications such as PCR setup, serial dilutions, and compound dispensing.
• Pipetting Accuracy: Maintains <3% error and coefficient of variation (CV) across the entire volume range, critical for reproducible liquid transfers in bioprocessing and clinical diagnostics.
• Throughput: Efficient handling with cycle times of approximately 2 minutes per 96-well plate, 3 minutes for 384-well copies, and 5 minutes for 4 x 384 plate stamp outs, supporting accelerated biomanufacturing workflows.
• Humidity Control: Integrated active humidity chamber maintaining 10–85% relative humidity to optimize sample stability during liquid handling, beneficial in sensitive live-cell imaging and fluorescence assays.
• Accessories: Includes spool cover for tip protection; pipette spools and consumables are sold separately. Disposable tips are used to eliminate cross-contamination risks, ensuring zero carry-over.
• Dimensions and Weight: Compact footprint with dimensions of approximately 79 x 47 x 69 cm (W x D x H) and a weight of 27 kg (59 lbs), suitable for benchtop installation in laboratory environments.

The workflow is controlled via dedicated Mosquito software enabling precise method setup, plate mapping, and run execution. The instrument has been verified for startup diagnostics, pipetting performance using gravimetric methodologies, plate alignment, and humidity chamber functionality.

This liquid handling system is widely adopted in biotechnology laboratories for assay miniaturization tasks critical in molecular cloning workflows, synthetic biology research, and high-throughput screening environments. The Mosquito HV enhances experimental reproducibility and operational efficiency in complex liquid dispensing protocols, offering robust support for biopharmaceutical production pipelines.

Its positive displacement mechanism effectively handles viscous and low-tension liquids, expanding its application scope across diverse molecular diagnostics and bioprocessing settings. The instrument’s capability to precisely dispense nanoliter to microliter volumes ensures minimal reagent consumption aligned with sustainability initiatives in modern laboratory practices.

Ideal applications include:

• High-density assay development and miniaturized PCR setup
• Precise serial dilutions and compound dispensing for drug discovery
• Automated plate stamping for rapid sample replication
• Essential tool for molecular biology and synthetic biology research requiring automated low-volume liquid handling

This SPT Labtech Mosquito HV Liquid Handler is a reliable, serviced, and fully functional pre-owned system with warranty and after-sales technical support available. It supports biotechnological innovation and clinical research by providing a bioscientific platform optimized for miniaturized liquid transfer and assay throughput enhancement.