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Qiagen TissueLyser II High-Throughput Bead Mill Homogenizer for Biological Samples

UsedQiagenHomogenisersUnited States

Price on request

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Throughput Capabilities
Adapter set 2 x 96: uses 1.2 ml collection microtubes (racked) up to 192 samples/run Or Adapter set 2 x 24: holds 24 x 2 ml microcentrifuge tubes per side, up to 48 samples/run
Typical Run Time
15 sec – x 3 minutes a 15-30 Hz
Timer
10 seconds to 99 minutes
Frequency
3-30 Hz /180-1800 oscillations/minute
Power
120V, 50-60Hz, 4A 100-240V, 50/60Hz, ~1.25A
All 9 specifications
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Specifications 9

Brands
Qiagen
New/Used
Used
Throughput Capabilities
Adapter set 2 x 96: uses 1.2 ml collection microtubes (racked) up to 192 samples/run Or Adapter set 2 x 24: holds 24 x 2 ml microcentrifuge tubes per side, up to 48 samples/run
Typical Run Time
15 sec – x 3 minutes a 15-30 Hz
Timer
10 seconds to 99 minutes
Frequency
3-30 Hz /180-1800 oscillations/minute
Dimensions
12” x 19” x 9” (TissueLyser) 14″ x 18″ x 10″ (TissueLyser II)
Weight
46lbs (TissueLyser) 59lbs (TissueLyser II)
Power
120V, 50-60Hz, 4A 100-240V, 50/60Hz, ~1.25A

Product description

The Qiagen TissueLyser II is a high-throughput, bead mill homogenizer engineered for parallel disruption of biological samples in tubes and 96-well plate formats. It delivers precise frequency control from 3 to 30 Hz (180-1800 oscillations/minute) and supports timed runs from 10 seconds up to 99 minutes, enabling tailored energy input crucial for molecular diagnostics, gene expression, and next-generation sequencing workflows.

Key technical features include:

  • Capacity to process up to 192 samples per run using the 2 x 96 microtube adapter set or 48 samples per run with the 2 x 24 adapter set for 2 ml tubes.
  • Designed to disrupt a broad range of biological materials such as human and animal tissues, plant materials, bacteria, and yeast using bead types like stainless steel, tungsten carbide, and acid-washed glass.
  • Advanced keypad control with 0.1 Hz frequency steps and memory for up to 9 programmable setups, enhancing reproducibility in high-throughput molecular biology applications.
  • Significantly reduced operational noise at 71 dB(A) compared to the original TissueLyser, supporting a quieter lab environment.
  • Compact footprint measuring 14″ x 18″ x 10″ and a weight of 59 lbs, with versatile power input of 100-240V, 50/60 Hz suitable for global laboratory settings.

The TissueLyser II is widely adopted across biotechnology and clinical diagnostics laboratories, serving as an essential instrument for high-throughput nucleic acid extraction and sample homogenization in bioprocessing and synthetic biology research. Its compatibility with Qiagen spin-column and magnetic-particle kits optimizes workflows essential for molecular cloning, biomanufacturing, and cellular analysis pipelines.

This model is engineered for durability and integration into automated workflows, providing consistent, high-quality sample input for downstream applications in biomedical engineering and translational research. It stands as a critical tool for laboratories seeking scalable performance in molecular biology and biotechnology sample preparation.

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Frequently asked questions

How long does laboratory equipment typically last?

With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.

Can I get service for older equipment?

Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.

Where can I buy parts?

Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.

What is the typical lead time for refurbished equipment?

Two to six weeks, depending on refurbishment scope and whether calibration is included.

Does laboratory equipment ship internationally?

We ship to 38 countries. Crating and customs handling are quoted with the instrument.

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Last updated 28 October 2026