Molecular Devices ImageXpress Ultra XLS High Content Confocal Plate Reader

The Molecular Devices ImageXpress Ultra XLS is a high content confocal plate reader designed for advanced fluorescence imaging and automated microscopy in biotechnology and molecular diagnostics. Equipped with multiple excitation lasers—Coherent 488 nm and 561 nm, as well as Blue Sky 408 nm and 630 nm—the system enables multiplexed fluorescence analysis essential for high-throughput screening and live-cell imaging applications.

• Confocal imaging technology provides high-resolution subcellular detail, critical in synthetic biology and cellular phenotyping workflows.
• The integrated beam splitter wheel and main stage support precise multi-well plate handling, aligning with bioprocessing and gene editing research needs.
• The Ultra XLS variant is tailored for seamless compatibility with multi-mode plate formats, optimizing throughput in molecular cloning and biopharmaceutical production pipelines.

While this unit exhibits a DSP 111 Y-axis initialization error, making it non-operational without repair, key components such as lasers and optical modules remain valuable for spare parts management in laboratories running ImageXpress high content imaging systems. This platform is widely adopted in biotechnology and biomedical engineering domains focused on fluorescence-based cell imaging, molecular biology assays, and drug discovery pipelines.