Agilent BioTek Synergy H1MG Multi-Mode Microplate Reader with Monochromator Optics

The Agilent BioTek Synergy H1MG Microplate Reader is a versatile multi-mode microplate reader designed for advanced quantitative analysis in molecular diagnostics, biotechnology, and biomedical research. It supports UV-Vis absorbance, fluorescence intensity, luminescence, fluorescence polarization, and time-resolved fluorescence detection modes, enabling comprehensive assay flexibility essential for gene editing workflows, enzyme kinetics, and bioprocessing applications.

Key features include:

• Quadruple grating monochromator system for flexible, wavelength-selective detection over wide ranges:
• Absorbance: 230–999 nm with 1 nm increments, 4 nm bandpass (230–285 nm), 8 nm (>285 nm)
• Fluorescence: 250–700 nm excitation/emission range via dual grating monochromators (top and bottom)
• Luminescence: 300–700 nm range, sensitive to 20 amol ATP (flash assays)
• Time-Resolved Fluorescence: 250–850 nm with europium sensitivity down to 1200 fM
• Read methods supporting endpoint, kinetic, spectral scanning, and well area scanning for precise assay measurements
• Compatible with common microplate formats: 6-, 12-, 24-, 48-, 96-, and 384-well, supporting high-throughput synthetic biology screens and clinical diagnostics
• Temperature control up to 45 °C with ±0.2 °C stability at 37 °C, enabling live-cell assay incubation and enzyme kinetics under controlled conditions
• Integrated shaking (linear, orbital, double orbital) to ensure assay homogeneity and reproducibility
• Dynamic detection ranges and high resolution:
• Absorbance up to 4.0 OD with 0.0001 OD resolution
• Fluorescence with 5-decade dynamic range and high sensitivity (Fluorescein detection at low pM levels)
• Luminescence with >6-decade dynamic range for sensitive reporter gene assays and bioluminescence studies
• Optional BioStack Microplate Stacker available for automated higher throughput workflows in biomanufacturing and drug screening
• Gas controller compatibility supports environmental control in live-cell imaging and cell-based assays

This instrument is widely adopted in molecular biology and biotechnology laboratories for ELISA, DNA/RNA quantification, cell viability assays, reporter gene analysis, enzyme kinetics, and toxicity screening. It is critical in biopharmaceutical production pipelines and molecular diagnostics workflows requiring flexible multi-mode optical detection with low cross-talk and high sensitivity.

The Synergy H1MG is fully serviced, tested, and comes with a warranty covering parts and labor, ensuring reliable operation. It is suitable for university research, clinical labs, and biopharma companies needing precise, reproducible microplate assay data. The instrument ships with communication and power cables; computer and Gen5 software must be procured separately.

Keywords: multi-mode microplate reader, monochromator optics, absorbance reader, fluorescence intensity reader, luminescence detection, time-resolved fluorescence, biotechnology instrumentation, molecular diagnostics, enzyme kinetics analysis, bioprocessing assay device, ELISA reader, live-cell assay incubator, biomedical engineering equipment.