Illumina NextSeq 500 High-Throughput Benchtop Sequencer for Genomics and Transcriptomics

The Illumina NextSeq 500 is a benchtop next-generation sequencer delivering high flexibility and throughput for comprehensive genomic and transcriptomic applications. Utilizing Sequencing by Synthesis (SBS) technology, it supports high-precision sequencing of whole genomes, exomes, and transcriptomes critical in biotechnology and clinical diagnostics.

Key technical features include:

• Throughput: Configurable for high flow cell (up to 400 million reads) or mid flow cell (up to 130 million reads) modes
• Read length: Up to 2×150 base pairs, enabling detailed sequencing of targeted regions such as exomes and gene panels
• Run time: Between 11 and 29 hours depending on sequencing configuration, suitable for time-sensitive molecular biology workflows
• Sample capacity: Supports sequencing of up to 16 exomes or 20 transcriptomes per run, enabling scalable bioprocessing and gene expression profiling
• Control interface: Intuitive touchscreen interface with integrated cloud and onsite data analysis through Illumina BaseSpace, facilitating streamlined workflow in molecular diagnostics and synthetic biology research
• Physical specs: Dimensions 58.5 × 53.4 × 63.5 cm; weight 83 kg

Compatibility with TruSeq preparation kits and BaseSpace analytics enhances its utility in biopharmaceutical production pipelines, molecular cloning workflows, and epigenetic methylation studies. The system is widely adopted in synthetic biology and biotechnology laboratories requiring rapid, accurate sequencing data for diverse genomic research and clinical applications.

Regular Product Care Silver Support maintenance ensures reliable performance with the latest preventive servicing completed in September 2024. The NextSeq 500 remains a robust, versatile instrument for research professionals demanding scalable, high-throughput sequencing solutions in molecular diagnostics, neurogenomics, and biomedical engineering domains.