Bruker Avance III 400

The Bruker Avance III 400 is a high-performance 400 MHz Nuclear Magnetic Resonance (NMR) spectrometer designed for detailed molecular analysis across various scientific disciplines. Introduced in 2007, this instrument remains a cornerstone in research laboratories, offering exceptional sensitivity and versatility for both routine and complex NMR experiments.

Key features include:

• High-resolution 400 MHz magnet for precise spectral data.
• Dual-channel configuration with advanced digital control for simultaneous multi-nuclei observation.
• Broadband probes capable of detecting a wide range of nuclei, including ¹H, ¹³C, ¹⁵N, ³¹P, and ¹⁹F.
• Z-axis gradient capabilities for enhanced pulse field gradient experiments.
• Temperature control systems allowing experiments from sub-zero to elevated temperatures.
• Automation options such as autosamplers for high-throughput sample analysis.

This spectrometer is extensively utilized in fields like organic chemistry, biochemistry, pharmaceutical research, and biotechnology. In biotechnology, it plays a pivotal role in protein structure determination, metabolomics, and drug discovery, providing critical insights into molecular interactions and dynamics.

Commonly found in university laboratories, biomedical research centres, and pharmaceutical companies, the Bruker Avance III 400 continues to be a reliable and versatile tool for scientists seeking detailed molecular characterisation.