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Reversed-phase C18 HPLC column, 25 cm × 4.6 mm, 5 µm particles, optimized for basic organic compounds, 0–70 °C, 400 bar.
The Supelco Supelcosil LC-18-DB (58355-U) is a high-performance reversed-phase liquid chromatography (HPLC) column designed for enhanced separation of basic organic compounds, widely used in biotechnology and molecular diagnostics workflows. Featuring a 25 cm length, 4.6 mm internal diameter, and 5 µm particle size, this C18 column integrates a specially deactivated silica phase (Type A) to reduce tailing and improve peak shape for organic bases. Its robust operation range supports temperatures from 0 to 70 °C and a maximum pressure of 400 bar (5801 psi), making it ideal for high-throughput and sensitive bioprocessing applications. This column is essential for researchers in synthetic biology and biomedical engineering requiring reliable chromatographic performance in chromatographic purification, gene editing product analysis, and biomanufacturing quality control. The Supelcosil LC-18-DB provides higher efficiency and shorter retention times compared to conventional reversed-phase silica columns, optimizing workflows in molecular cloning and fluorescence analysis studies.
This LC column is a critical tool for analytical chemistry labs focused on biopharmaceutical production pipelines and complex cell imaging assay development.
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With a service contract, ten to fifteen years is normal for most benchtop instruments. Detectors and pumps are the parts that wear first.
Often, yes. Verified suppliers frequently work with service partners converting the instrument. If applicable, we can list servicing options alongside the offer.
Ask a scientist through the request button. Parts are often available even when the instrument itself is discontinued.
Two to six weeks, depending on refurbishment scope and whether calibration is included.
We ship to 38 countries. Crating and customs handling are quoted with the instrument.
Tell us what you need and a scientist finds it for you, usually within the hour.
Last updated 22 October 2026
The middle half of the 78 with a price runs from €250 to €529.
