BD Rhapsody Scanner Single-Cell Analysis System with Rhapsody Express for High-Throughput Multiomic Profiling

The BD Rhapsody Scanner Single-Cell Analysis System is a microwell-based, high-throughput platform designed for multiplexed single-cell multiomic profiling essential in molecular diagnostics, biotechnology, and bioprocessing research. The system integrates the Rhapsody Scanner (Ref: 633701) with the Rhapsody Express System (Ref: 633702) to enable efficient capture and quality control of single cells for next-generation sequencing (NGS) library preparation.

Key technical features include:

• Microwell technology: 220,000 microwell partitions per cartridge support capturing between 100 and 40,000 single cells per run.
• High capture rates: Achieves up to 90% cell capture efficiency at lower throughput (10,000 cells), sustaining 83% capture at 40,000 cells, critical for gene expression and protein profiling.
• Multiplet rates: Maintains low multiplet rates of approximately 2–3% at 10,000 cells, with acceptable increases at higher cell loads, important for accurate single-cell data integrity.
• Gentle Gravity-based Cell Capture: Enables processing of fragile cell types such as granulocytes, CAR-T cells, stem cells, and tumor xenograft-derived cells, minimizing cell stress and preserving cellular phenotype—vital for advanced synthetic biology and immune cell heterogeneity studies.
• Benchtop design: Compact footprint with integrated visual QC scanner for cell capture verification and barcode-based cell/sample identification enhances experimental reliability and flexibility for biotechnology workflows.
• Compatibility: Supports multiplex antibody and sample barcoding, bead-based mRNA capture, and integration into BD’s established sequencing workflows widely adopted in biopharmaceutical production pipeline and molecular cloning workflows.
• Loading volume: 575 µL cell suspension per cartridge, streamlined for efficient sample processing in research labs.

The system undergoes comprehensive performance verification including touchscreen functionality, bead loading and washing, motion control, internal camera calibration, and fluidics inspection to ensure reproducible results and long-term stability. This instrumentation is widely used in biological research applications such as tumor microenvironment characterization, rare cell population identification, and immune profiling, making it an indispensable tool in molecular biology, clinical diagnostics, and biomedical engineering laboratories.

This pre-owned BD Rhapsody system is fully serviced, backed by a 120-day US warranty and 60-day international warranty, catering to universities and biopharma companies requiring reliable single-cell multiomic sequencing preparation solutions.

Keywords incorporated: single-cell analysis system, microwell-based single-cell capture, high-throughput multiomic profiling, single-cell RNA sequencing, immune cell heterogeneity, gene expression profiling, molecular diagnostics, bioprocessing research, synthetic biology workflows, biopharmaceutical production pipeline, tumor microenvironment study, multiplexed antibody barcoding, benchtop single-cell scanner, visual quality control scanner.