Eppendorf BioFlo 320 Bioprocess Bioreactor Control System with 1 SLPM Gas Flow Control

The Eppendorf BioFlo 320 Bioprocess Control System is a versatile and compact bioreactor controller designed to support both microbial fermentation and cell culture applications in biotechnology research and biopharmaceutical production. Equipped with advanced temperature, pH, dissolved oxygen (DO), and gas flow control features, this system is widely adopted in upstream bioprocessing workflows, including molecular diagnostics and synthetic biology research.

Key technical features include:

• Gas flow control via Thermal Mass Flow Controllers (TMFC) for up to 4 gases (Air, N2, O2, CO2) with selectable flow ranges from 0.002 to 1.0 SLPM (standard) and options up to 20 SLPM
• Compatibility with autoclavable glass vessels (sizes 1.0L to 10L) and Eppendorf BioBLU single-use bioreactors (volumes from 380 mL to 50 L), enabling scalable bioprocess development
• Integrated four Watson-Marlow peristaltic pumps with variable and fixed speed modes for precise media feeding and sampling, supporting continuous culture and fed-batch processes
• Multiple digital sensor input ports accepting PT100 temperature probes and sensors for pH, DO, Redox, and CO2, allowing comprehensive real-time process monitoring
• Modular design supporting vessel drives (direct or magnetic) adjusted to vessel volume and type, with options for heating blankets especially suited for single-use vessels
• Exhaust condenser compatibility with liquid-cooled or Peltier cooling systems, ensuring stable temperature conditions during long bioprocess runs
• Touchscreen interface providing intuitive control and integration of smart sensors, facilitating efficient operation in bioprocess scale-up and optimization studies

Additional capabilities include level and foam sensors, optional optical pH probes, vessel scales for content weight measurement, and external pump integration. The system operates on 100–240 VAC power, with dimensions of 40.6 cm (W) × 40.6 cm (D) × 66.0 cm (H) and a net weight of 32 kg.

Applications span cell culture growth optimization, microbial fermentation process development, and biopharmaceutical production pipelines, making the BioFlo 320 critical for laboratories engaged in bioprocessing, gene editing, synthetic biology, and molecular cloning workflows.

This unit is thoroughly tested for sensor accuracy, motor control stability, pump performance, and gas flow reliability to ensure full functionality and compliance with stringent lab standards. Available warranty coverage, remote technical support, and optional on-site training enhance dependability for research professionals.

By supporting both autoclavable and single-use vessel formats, the BioFlo 320 Bioprocess Control System provides versatile process control essential for live-cell imaging preparation, fluorescence analysis bioprocesses, and other laboratory-scale biotechnology applications.

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