Promega Maxwell RSC 48 AS8500 Automated DNA/RNA Purification System for High-Throughput Sample Processing

The Promega Maxwell RSC 48 AS8500 is an automated benchtop DNA/RNA purification system designed to process up to 48 samples simultaneously with consistent nucleic acid yield and purity. It employs magnetic particle-based technology to efficiently extract genomic DNA, total RNA, and viral nucleic acids from various sample types, supporting workflows essential in molecular diagnostics, gene editing, and bioprocessing applications.

Key features include:

• High-throughput capacity: Processes 1 to 48 samples in removable dual 24-position trays, optimizing medium- to high-throughput laboratory workflows for molecular cloning and synthetic biology research.
• Automated workflow: Minimizes hands-on time through the use of prefilled reagent cartridges, reducing contamination risk and ensuring reproducibility in nucleic acid extraction.
• Advanced software integration: Includes intuitive Maxwell 48 RSC Application Software (ver 3.0.1) on a Windows tablet PC with a vision system for deck tray setup error detection, enhancing reliability and ease of use.
• Quantitation compatibility: USB port allows integration with Promega Quantus Fluorometer for precise sample concentration assessment post-extraction, critical for downstream sequencing and molecular biology applications.
• Compact benchtop design: Dimensions of 21 × 21 × 14 inches and weight ~60 lbs (27 kg), suitable for laboratories requiring efficient use of bench space.
• Robust instrument verification: Includes self-test functions, heater validation, UV bulb operation, and door motion detection to ensure operational integrity before runs.

The Maxwell RSC 48 system is widely adopted in molecular biology, clinical diagnostics, and biotechnology fields requiring automated and reproducible nucleic acid purification for applications such as next-generation sequencing, biopharmaceutical production pipelines, and viral RNA isolation. Its magnetic particle extraction approach offers a reliable solution for automated sample preparation in gene editing and synthetic biology research.

This instrument supports biosample processing needs ranging from genomic DNA extraction to RNA cleanup, making it essential for laboratories engaged in biotechnology, molecular diagnostics, and bioprocessing workflows seeking to enhance throughput and reproducibility.