Thermo Fisher CTS DynaCellect Automated Magnetic Cell Separation System for Cell Therapy

The Thermo Fisher CTS DynaCellect Magnetic Separation System is an advanced automated magnetic cell separator designed for closed-system cell processing applications in biotechnology and clinical research. It enables high-purity (>95%) isolation and depletion of target cell populations using CTS Dynabeads CD3/CD28 with an isolation efficiency greater than 85%. The system supports scalable bioprocessing up to 1,000 mL working volume (~10 billion T cells input) and unlimited bead removal scale, verified up to 10 L, ideal for cell therapy manufacturing and molecular diagnostics in compliance with cGMP standards.

Key features include:

• Automated closed magnetic separation with integrated magnet-rocker and fluidics for consistent cell processing.
• Precise control over flow rates (10–150 mL/min), rocker angle (−30° to 30°), and rocker speed (1–30 cycles per minute) to optimize cell isolation and viability.
• Compatibility with the DeltaV™ system (OPC-UA) for integration into automated biomanufacturing pipelines.
• Use of sterile, single-use flow paths minimizing contamination risk, critical in cell therapy production and synthetic biology research.
• Compact benchtop design with a footprint of 56.2 x 75 x 48.5 cm and weight of 50 kg, suitable for both small- and large-scale bioprocessing workflows.
• Robust performance metrics: coefficient of variation (CV) of 3% for reproducibility and cell viability remains unaffected throughout processing.
• Equipped with peristaltic pump, 11 pinch valves, bubble and pressure sensors, and essential hardware for closed-system operation.

This system is widely adopted in molecular biology and biotechnology research for live-cell isolation, cell depletion, and bead removal steps necessary in gene editing, synthetic biology, and biopharmaceutical production pipelines. Its reliability and scalability make it essential for researchers and medical professionals engaged in advanced cell therapy development and immunology assay preparation.

The CTS DynaCellect system requires professional installation and setup, ensuring precise integration into your laboratory environment. Pre-owned units undergo rigorous in-house testing to verify full functionality, including rocker angle calibration, valve operation, pump performance, and emergency stop systems, providing confidence for clinical and research applications.

This instrument connects seamlessly to existing laboratory workflows and supports critical cell isolation protocols necessary for molecular cloning workflows and bioprocess engineering in academic and industrial laboratories specializing in clinical diagnostics and biomanufacturing.

Primary keywords: automated magnetic cell separator, cell therapy magnetic separation, closed-system cell isolation, CTS DynaCellect Long-tail keyword phrases: scalable magnetic cell separation system for bioprocessing, high-purity T cell isolation instrument for molecular diagnostics, automated closed magnetic separation system for biopharmaceutical production Domain-specific keywords: cell isolation, cell depletion, sterile single-use flow paths, recombinant biologics manufacturing, synthetic biology research, bioprocess control with DeltaV integration, cGMP-compliant cell processing