Thermo Dionex ASE 350 Accelerated Solvent Extractor for High-Throughput Sample Preparation

The Thermo Dionex ASE 350 Accelerated Solvent Extractor automates the extraction, filtration, and cleanup of solid and semisolid samples, making it ideal for high-throughput laboratories engaged in molecular diagnostics, biotechnology, and chemical analysis. This system processes up to *24 samples unattended*, optimizing laboratory workflows essential in bioprocessing and synthetic biology research.

Key features include:

• Temperature control up to 200°C with precise regulation for efficient extraction of organic and aqueous compounds
• Maximum operating pressure of 1500 psi (10 MPa) for enhanced solvent penetration
• Rapid solvent pump delivering 70 mL/min flow rate, facilitating fast extraction cycles (12-20 minutes)
• Supports a broad range of sample sizes from 1 to 100 grams utilizing interchangeable extraction cells (1, 5, 10, 22, 34, 66, 100 mL)
• Chemically inert solvent pathway compatible with both acidic and alkaline matrices, ensuring sample integrity for molecular cloning workflows
• Integrated solvent controller capable of mixing and delivering up to three solvents, reducing solvent consumption by 50-90% via solvent saver mode
• Pneumatic requirements tailored for air and nitrogen supply to enable stable operating conditions

Constructed for durability, the ASE 350 weighs approximately 152 kg (336 lbs) and fits within standard laboratory space constraints. It is widely adopted in biopharmaceutical production pipelines and clinical diagnostics laboratories where robust, automated solvent extraction accelerates sample preparation.

This unit powers on and initializes with no errors; however, full functional testing including temperature, pressure, and extraction performance requires connection to the control software (not included). Overall, the ASE 350 is a critical instrument for efficient, reproducible solvent extraction in biotechnology and chemical research environments.