Thermo Fisher CTS DynaCellect Automated Magnetic Cell Separation System A52299

The Thermo Fisher CTS DynaCellect Magnetic Separation System (Ref. A52299) is an automated, closed-system instrument designed for high-efficiency magnetic cell separation in research and biomanufacturing applications. It facilitates the isolation, depletion, and bead removal of defined cell populations using sterile single-use flow paths, supporting cGMP-compliant workflows essential for molecular diagnostics and cell therapy development.

Key technical specifications include:

• Processing time: 70–100 minutes with reproducibility (CV 3%)
• Isolation efficiency: >85% (using CTS Dynabeads CD3/CD28) with 95% purity and unaffected viability
• Maximum scale: Up to 1,000 mL working volume (~10 billion T cells input), verified bead removal up to 10 L
• Pump speed range: 10–150 mL/min controls fluidics precisely during separation steps
• Rocker capabilities: Adjustable angle from -30° to 30°, rocker speed 1–30 cycles per minute for optimal mixing
• Compatibility: DeltaV™ system (OPC-UA) enables integration into automated bioprocessing pipelines
• Power requirements: 100–240 V AC, 600 W; weighs 50 kg with compact dimensions of 56.2 x 75 x 48.5 cm

The system integrates a magnet-rocker assembly and peristaltic pump with multiple pinch valves, bubble and pressure sensors to ensure controlled magnetic engagement and fluid handling. Its design supports closed, sterile manipulation of cells critical in synthetic biology, gene editing workflows, and advanced biomanufacturing processes.

This magnetic separation system is widely used in biotechnology for live-cell isolation, T cell processing, and molecular cloning workflows, offering scalable throughput for translational research and clinical diagnostics. The instrument’s automated functionality reduces manual steps and enhances reproducibility—critical for high-demand bioprocessing environments.

Technical sales consultation, installation support, and warranty services are available, ensuring smooth integration into laboratory and production settings. Consumables supplied separately include CTS™ DynaCellect Cell Isolation and Bead Removal Kits and specialized Dynabeads.

This system is essential for researchers and professionals requiring robust, scalable magnetic cell separation solutions in neuroscience, cell imaging, immunotherapy development, and biomedical engineering sectors.