Thermo Applied Biosystems Automated Thermal Cycler (ATC) with 384-well Isothermal PCR Block

The Thermo Applied Biosystems Automated Thermal Cycler (ATC) is a high-performance 384-well PCR thermal cycler designed for precise temperature control and rapid cycling essential for molecular biology, biotechnology, and clinical diagnostic applications. Featuring an isothermal 384-well block compatible with full-skirted plates, it supports PCR volumes of 5–10 µL with exceptional thermal accuracy (±0.25°C from 35°C to 99.9°C) and uniformity (<0.5°C within 20 seconds at 95°C). The instrument operates over a wide thermal range of 0–105°C with maximum ramp rates up to 2.8°C/sec (block) and 1.6°C/sec (sample), enabling rapid heating and cooling cycles tailored for high-throughput gene amplification, SNP genotyping, qPCR, cloning, sequencing preparation, and other bioprocess workflows.

The ATC incorporates automated lid operation and programmable protocols to reduce manual intervention, optimizing workflow integration in molecular diagnostics and synthetic biology research environments. Its robust design and reliable performance meet demanding lab standards across biopharmaceutical production pipelines and molecular cloning workflows. The included software interface allows for intuitive control and seamless connectivity with the supplied laptop, enhancing data accuracy and reproducibility critical in gene expression analysis and genetic screening.

Key technical features include:

• 384-well isothermal block compatible with 20 µL full-skirted PCR plates
• Thermal accuracy of ±0.25°C ensuring reproducible amplification results
• Rapid ramp rates of 2.8°C/sec for block and 1.6°C/sec for samples for efficient protocol turnaround
• Wide temperature range (0–105°C) supporting diverse PCR protocols including qPCR and SNP genotyping
• Automated lid and programmable workflow settings for hands-free operation
• Precise thermal uniformity (<0.5°C at 95°C) critical for high-throughput molecular diagnostics

This system is widely adopted in biotechnology, molecular cloning, and biomanufacturing, providing essential capabilities for gene editing verification, synthetic biology research, and clinical molecular diagnostics. It is engineered for longevity, reliability, and is backed by comprehensive servicing and warranty options. The package includes the thermal cycler block module, control module, dedicated laptop with control software, and all necessary power and communication cables, making it ready for immediate deployment in research and bioprocessing labs.

By integrating this Automated Thermal Cycler into your laboratory, you benefit from increased throughput and precise thermal control—key factors in successful PCR workflows and molecular biology research essential to biotechnology innovation and biopharmaceutical production pipelines.