Nikon Eclipse TI-E Inverted Fluorescence Motorized Phase Contrast Microscope with Motorized XY Stage

The Nikon Eclipse TI-E is a high-performance *inverted fluorescence microscope* equipped with a comprehensive motorized system ideal for biotechnology, cell biology, and clinical diagnostics. This model integrates precision automation essential for applications requiring live-cell imaging, fluorescence analysis, and multidimensional microscopy.

Key features include:

• Microscopy techniques: Brightfield, phase contrast, and fluorescence microscopy with optional DIC and polarization add-ons.
• Motorized components: Automated Z-axis focus drive, motorized XY stage controlled via joystick and LEP MAC6000 controller, motorized filter cube turret with six positions, and motorized 6-position nosepiece objective turret.
• Fluorescence illumination: EXFO X-Cite 120 Metal Halide light source with collimating adapter and light guide, supporting multiple high-precision fluorescence filter sets (DAPI, FITC/EGFP, TRITC/Cy3, Texas Red, Cy5 compatible).
• Objectives: Equipped with high-quality Plan Fluor and CFI Plan Apo VC objectives (4x/0.13, 10x/0.30, 20x/0.75), offering enhanced optical resolution and contrast for detailed cellular and subcellular imaging.
• Condenser: Mechanical condenser (TI-C) with long working distance (LWD 0.52) and phase contrast inserts (PhL, Ph1).
• Imaging: Includes a Bestscope 8.3 MP color CMOS camera with C-mount adapter, paired with Dell Windows 10 laptop running Micromanager and ImageJ software for multi-frame, multi-slice (Z-stacking), and multi-position image acquisition.
• Applications: Widely adopted in biotechnology research fields such as molecular diagnostics, gene editing, synthetic biology, and bioprocessing workflows. Supports studies in pharmacology, neuroscience, material science, and biomedical engineering through high-resolution imaging and fluorescence quantification.
• Automation benefits: Automated focus recall with parfocality correction improves efficiency in long-term live-cell and time-lapse experiments while motorized stages enable precise multi-sample imaging, crucial for biopharmaceutical production pipelines and multi-well plate screening.

The microscope undergoes rigorous preventive maintenance and optical verification ensuring optimal fluorescence intensity, optical uniformity, and functionality of motorized parts. It includes a 180-day continental USA warranty and remote training for seamless integration into laboratory workflows.

This system is customizable for enhanced magnification up to 1000x, advanced fluorescence light sources (LED, Xenon), and higher-performance cameras (CCD, sCMOS, EMCCD) to suit specific biotechnological applications requiring critical imaging precision and repeatability.

Ideal for researchers demanding robust, motorized inverted fluorescence microscopy solutions in molecular biology, live-cell imaging, synthetic biology, and clinical diagnostics.