Agilent BioTek EL406 406PSUB3 Automated Microplate Washer Dispenser with Ultrasonic and Dual Syringe Pumps

The Agilent BioTek EL406 Microplate Washer Dispenser 406PSUB3 is an integrated automated system designed for high-precision microplate washing and reagent dispensing in 96- and 384-well formats. It combines advanced liquid handling technologies, including dual syringe pumps and a built-in peristaltic pump, with ultrasonic cleaning to deliver clog-free, reproducible results essential for molecular diagnostics, biotechnology research, and bioprocessing applications.

Key technical features include:

• Plate Compatibility: Supports standard 96- and 384-well microplates; syringe manifolds can be upgraded for 6- to 1536-well plates, addressing a broad range of assay throughput needs.
• Dispensing Volume Range:
• Peristaltic pump: 1–3000 µL with typical precision <3% CV at 1 µL/well
• Washer 96-tube manifold: 50–3000 µL with <3.0% CV at 300 µL/well
• Optional 192-tube manifold for faster 384-well washing, supporting volumes 25–5000 µL.
• Washing Functionality:
• Selectable wash parameters with dual-action 96-tube manifold enabling independent dispensing and aspiration control for improved wash efficiency and crosswise aspiration reducing residue.
• Ultrasonic Advantage technology prevents nozzle clogging, maintaining consistent performance during repetitive assays.
• Supports soaking, shaking, and sonication protocols, optimizing wash steps for ELISA, cell-based, bead-based, and vac-filtration assays.
• Dispensing Technology: Combines syringe pumps, peristaltic pump, and wash head dispensing to manage up to three dispensing liquids plus one wash buffer; optional valve modules enable up to four buffer switching.
• Software and Interface: Compatible with LHC software for method creation and integration into laboratory workflows, facilitating automation in molecular biology, synthetic biology, and molecular cloning pipelines.
• Accessories and Options: Includes tubing kits, source and waste bottles, vacuum pump, with optional BioStack plate stackers and manifold upgrades enhancing throughput and flexibility.
• Service and Validation: Pre-owned units are thoroughly inspected, cleaned, mechanically adjusted, and electrically tested; volumetric accuracy is verified across micro- and milliliter ranges to ensure precise dispensing and washing essential in biopharmaceutical production pipelines.
• Applications: Widely adopted for ELISA, Meso Scale Discovery (MSD) assays, PCR setup with microvolume dispensing, serial dilutions, plate coating, and bead-based immunoassays; critical in biotechnology research fields such as gene editing, molecular diagnostics, and biomanufacturing.

This model's reliable hardware interface with physical buttons (preferred by some users over touchscreens) offers robust performance and a space-saving footprint suitable for laboratories focusing on biologics development, neuroscience applications, and clinical diagnostics workflows. The ultrasonic cleaning combined with precise liquid handling minimizes well-to-well variability, making it an essential instrument for high-throughput screening and synthetic biology research.

Overall, the Agilent BioTek EL406 combines advanced microplate washing and dispensing with customizable modules, allowing efficient integration into diverse laboratory environments requiring reproducible assay preparation and bioprocess optimization.

---

Primary Keywords: microplate washer dispenser, automated microplate washer, syringe pump dispenser, ultrasonic microplate washer Long-Tail Phrases Incorporated: precise syringe pump dispensing for molecular diagnostics, clog-free ultrasonic microplate washing, essential for molecular cloning workflows, widely adopted in synthetic biology research, critical in biopharmaceutical production pipelines, reliable microplate washer dispenser for ELISA and cell-based assays