Teledyne ISCO CombiFlash EZ Prep UV Preparative Flash Chromatography System with Dual Pumps and UV Detection

The Teledyne ISCO CombiFlash EZ Prep UV Preparative Flash Chromatography System is a precision-engineered platform designed for rapid and reproducible purification of synthesized organic compounds, natural products, and pharmaceutical samples. Widely adopted in synthetic biology research and molecular diagnostics, this system integrates flash chromatography and preparative HPLC capabilities combined with UV detection for accurate compound monitoring.

Key technical features include:

• Flow rate range: 5–200 mL/min with ±5% accuracy
• Pressure capabilities: up to 3500 psi (240 bar) in high-pressure mode and 200 psi (13.8 bar) in flash mode
• Binary gradient control: programmable linear, step, and isocratic gradients with ±3% accuracy between any two of four solvents
• UV detection: wavelength range 200–400 nm in ±5 nm increments for precise compound analysis
• Dual pump configuration: enables smooth gradient delivery essential for bioprocessing workflows and chromatography applications in biopharmaceutical production pipelines
• Compatibility: supports a wide range of column sizes and media, facilitating flexible purification strategies critical in synthetic biology and molecular cloning workflows

The system features a user-friendly touchscreen interface for automated flow control, fraction collection coordination, and seamless integration in biotechnology laboratories. Additional advantages include RFID column detection, automated fraction control, and consistent gradient reproducibility which are vital for molecular biology researchers and clinical diagnostics applications. The compact footprint (43 × 43 × 67 cm) and reliable power supply requirements (100–240 VAC, 50/60 Hz) make it suitable for various laboratory environments focused on biomanufacturing and synthetic biology.

This instrument undergoes comprehensive testing covering pump calibration, solvent delivery accuracy, UV lamp performance, and gradient stability to ensure baseline stability and reproducibility for sensitive biotechnological separations. The system supports purification of complex mixtures, fractionation of metabolites, and cleanup of crude pharmaceutical samples, making it an essential tool in biotechnology research and development.

Accessories such as multiple collection racks, solvent filters, and waste hoses are included, with optional columns and racks available to customize workflows. The system’s warranty and after-sales support provide peace of mind for long-term, demanding laboratory use.

Overall, the CombiFlash EZ Prep UV system is a critical preparative chromatography solution widely used in biotechnology, molecular biology, and biopharmaceutical production pipelines for high-throughput and reliable compound purification.