Agilent 1260 Infinity Fluorescence Detector G1321B Spectra for HPLC and UHPLC

The Agilent 1260 Infinity Fluorescence Detector G1321B Spectra is a precision analytical instrument designed for high-sensitivity fluorescence detection in HPLC and UHPLC applications. Equipped with an 8 µL flow cell and proprietary firmware A.07.02, this detector enables simultaneous multi-wavelength spectral acquisition, providing quantitative data and fluorescence spectra from single injections.

Key technical features include:

• Rotating gratings for multichannel spectral acquisition without sensitivity loss
• Exceptional detection limits with Raman signal-to-noise ratio (S/N) exceeding 3000, referenced to dark signal noise
• Simplified optical design to optimize baseline stability, critical for reproducible molecular diagnostics and bioprocessing workflows
• Data acquisition rate up to 145 Hz supporting ultra-fast liquid chromatography without compromise in resolution or sensitivity
• Long-life xenon flash lamp exceeding 4000 hours, ensuring consistent fluorescence excitation for extended biopharmaceutical production pipelines
• Front-accessible flow cell allows rapid inspection or replacement, facilitating uninterrupted synthetic biology and molecular cloning analyses

This fluorescence detector is widely adopted in biotechnology laboratories requiring sensitive and selective detection for gene editing validation, live-cell fluorescence assays, and fluorescence-based quality control in biomanufacturing. Its spectral capabilities aid in rapid method optimization and inline verification of separation quality, making it essential for advanced fluorescence analysis in both research and clinical diagnostic settings.